11 Results for "

Silymarin

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Silymarin" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-N7073
CAS No.: 65666-07-1
Silymarin is an extract of the milk thistle (Silybum marianum). Silymarin is an effective SARS-CoV-2 main protease (M pro) inhibitor. Silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance. Silymarin has the chemopreventive effect on hepatocellular carcinoma (HCC). Silymarin has the potential for COVID-19 research .
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2
2 Cited Publications
Cat. No.: HY-N7043
CAS No.: 142796-21-2
Isosilybin A is a PPARγ agonist that can be isolated from silymarin. Isosilybin A activates extrinsic and intrinsic pathways of apoptosis through targeting of the Akt-NF-kB-AR axis. Isosilybin A can relieve the inflammatory response in the rosacea model via inhibiting Erk and p38 signaling pathways and M1 macrophage polarization, with its targets related to RELA and VEGFA. Isosilybin A has anti-prostate cancer (PCA) activity [1][2][3].
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1
1 Cited Publications
Cat. No.: HY-N0646
CAS No.: 29782-68-1
Silydianin is a flavonolignan. Silydianin can be obtained from Silybum marianum. Silydianin inhibits PTP1B with an IC50 of 17.38 μM. Silydianin inhibits both monophenolase and diphenolase of tyrosinase significantly, with IC50s of 2.6 μM and 16.5 μM, respectively. Silydianin induces Apoptosis and reduces cytokines (IL-4 and IL-5). Silymarin has antioxidant, cytoprotective and immunomodulatory effects. Silydianin has antitumor activity against prostate cancer. Silymarin can be used in allergic asthma research .
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Cat. No.: HY-W043277
CAS No.: 62921-74-8
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG3-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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Cat. No.: HY-114661
CAS No.: 62921-76-0
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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Cat. No.: HY-W042501
CAS No.: 80755-67-5
Target:  

PROTAC Linkers

Research Areas:  

Cancer

m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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Cat. No.: HY-N13245
Target:  

SARS-CoV

Research Areas:  

Others

Milk Thistle Extract is the extract of Milk Thistle, with content of 80% Silymarin.
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Cat. No.: HY-177838
Target:  

Liposome

Research Areas:  

Metabolic Disease

Liposomal Silymarin is a specialized delivery system that encapsulates silymarin within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of silymarin. Silymarin is a natural flavonoid compound derived
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Cat. No.: HY-N0646R
CAS No.: 29782-68-1
Silydianin (Standard) is the analytical standard of Silydianin (HY-N0646). This product is intended for research and analytical applications. Silydianin is a flavonolignan. Silydianin can be obtained from Silybum marianum. Silydianin inhibits PTP1B with an IC50 of 17.38 μM. Silydianin inhibits both monophenolase and diphenolase of tyrosinase significantly, with IC50s of 2.6 μM and 16.5 μM, respectively. Silydianin induces Apoptosis and reduces cytokines (IL-4 and IL-5). Silymarin has antioxidant, cytoprotective and immunomodulatory effects. Silydianin has antitumor activity against prostate cancer. Silymarin can be used in allergic asthma research .
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Cat. No.: HY-135090
CAS No.: 82217-01-4
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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Cat. No.: HY-N7043R
CAS No.: 142796-21-2
Isosilybin A (Standard) is the analytical standard of Isosilybin A (HY-N7043). Isosilybin A is a PPARγ agonist that can be isolated from silymarin. Isosilybin A activates extrinsic and intrinsic pathways of apoptosis through targeting of the Akt-NF-kB-AR axis. Isosilybin A can relieve the inflammatory response in the rosacea model via inhibiting Erk and p38 signaling pathways and M1 macrophage polarization, with its targets related to RELA and VEGFA. Isosilybin A has anti-prostate cancer (PCA) activity [1][2][3].
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