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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Succinyl-CoA
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Succinyl-CoA" in MCE Product Catalog:
Synonyms: Succinyl-coenzyme A; S-(Hydrogen Succinyl)coenzyme A
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14 Publications Verification
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5 Cited Publications
Synonyms: Succinyl-CoA sodium
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
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Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Succinyl-CoA synthetase is a mitochondrial matrix enzyme and catalyst. Succinyl-CoA synthetase supports TCA, ketone and heme metabolism and is activated by mitochondrial phosphate. Succinyl-CoA synthetase distributes broadly across mammalian tissues with distinct substrate-related biochemical features. Succinyl-CoA synthetase gains structural stability after phosphorylation and relies on SUCLG1-encoded subunit for activity. Succinyl-CoA synthetase malfunction links to metabolic and neurological disorders. Succinyl-CoA synthetase serves as a research tool for mitochondrial hepatoencephalomyopathy .
Cat. No.: HY-173527
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PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders .
Synonyms: IsoSuccinyl coenzyme A tetralithium; Methylmalonyl coenzyme tetralithium
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
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Cat. No.: HY-12688
CAS No.: 26647-82-5
Cat. No.: HY-W973644
CAS No.: 147104-27-6
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LY-266500 is a succinyl CoA synthetase (SCS) specific inhibitor. LY-266500 has inhibitory effects on various parasites, such as Trypanosoma brucei brucei (IC50 =0.6 μM) and Leishmania donovani (IC50 =2.86 μM). LY-266500 can be used for research on parasitic infections .
Cat. No.: HY-CE00006
Synonyms: (1-Methylpentyl)Succinyl-coenzyme A
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(1-Methylpentyl)succinyl-CoA ((1-Methylpentyl)succinyl-coenzyme A) is a a higher alkylsuccinyl-CoA .
Cat. No.: HY-CE00290
CAS No.: 2857175-73-4
Synonyms: (2S)-2-((R)-Hydroxybenzyl)Succinyl-coenzyme A
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(R,S)-(Hydroxy(phenyl)methyl)succinyl-CoA ((2S)-2-((R)-Hydroxybenzyl)succinyl-coenzyme A) is a [hydroxy(phenyl)methyl]succinyl-CoA.
Cat. No.: HY-148285A
CAS No.: 403982-65-0
Synonyms: Succinyl-coenzyme A disodium; S-(Hydrogen Succinyl)coenzyme A disodium
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Succinyl CoA (Succinyl-coenzyme A) disodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA disodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA disodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA disodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl-Coenzyme A sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
Cat. No.: HY-CE01911
CAS No.: 1383686-26-7
Synonyms: [Hydroxy(phenyl)methyl]Succinyl-coenzyme A
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[Hydroxy(phenyl)methyl]succinyl-CoA ([Hydroxy(phenyl)methyl]succinyl-coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-CE00712
CAS No.: 830357-87-4
Synonyms: Naphthyl-2-methyl-Succinyl-CoA
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2-(2-Naphthylmethyl)succinyl-CoA (Naphthyl-2-methyl-succinyl-CoA) is a coenzyme A derivative.
Cat. No.: HY-CE01613
Synonyms: Naphthyl-2-methylene-Succinyl-coenzyme A
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Naphthyl-2-methylene-succinyl-CoA (Naphthyl-2-methylene-succinyl-coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-CE01614
CAS No.: 950761-58-7
Synonyms: Naphthyl-2-oxomethyl-Succinyl-coenzyme A
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Naphthyl-2-oxomethyl-succinyl-CoA (Naphthyl-2-oxomethyl-succinyl-coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-E71777
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3-Oxoadipyl-CoA thiolase (EC 2.3.1.174) is a transferase that can convert succinyl-CoA and acetyl-CoA into 3-oxoadipyl-CoA and CoA.
Cat. No.: HY-E71906
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5-Aminolevulinate synthase (EC 2.3.1.37) is a transferase that can convert succinyl-CoA, glycine and H + into 5-aminolevulinate, CO2 and CoA.
Cat. No.: HY-E71773
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3-Oxoacid CoA-transferase (EC 2.8.3.5) is a mitochondrial CoA transferase that generates acetoacetyl-CoA by transferring the CoA group from succinyl-CoA to acetoacetic acid.
Cat. No.: HY-180786
CAS No.: 3085711-53-8
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DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma .
Cat. No.: HY-P702784
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: OXCT1; SCOT-S; Prev. OXCT; Epididymis Secretory Sperm Binding Protein; SCOT; Succinyl-CoA:3-Ketoacid CoA Transferase; Succinyl-CoA:3-Ketoacid Coenzyme A Transferase 1, Mitochondrial; Succinyl CoA:3-Oxoacid CoA Transferase; Somatic-Type Succinyl-CoA:3-Oxoa
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
