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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
TEM-1
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "TEM-1" in MCE Product Catalog:
94
94 Publications Verification
Synonyms: NXL-104
Target:
Research Areas:
Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively [1].
94
94 Publications Verification
Synonyms: NXL-104 free acid
Target:
Research Areas:
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively [1].
94
94 Publications Verification
Synonyms: NXL-104 hydrate
Target:
Research Areas:
Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively [1].
Cat. No.: HY-P99778
CAS No.: 946415-62-9
Synonyms: MORAb-004
Cat. No.: HY-14879AR
CAS No.: 1192491-61-4
Synonyms: NXL-104 (Standard)
Research Areas:
Avibactam (sodium) (Standard) is the analytical standard of Avibactam (sodium). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively [1].
Synonyms: Cyclohexyl-hexyl-β-D-maltoside
Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an Ki value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant [1] .
Cat. No.: HY-14879S2
Synonyms: NXL-104-13C5
Cat. No.: HY-U00380
CAS No.: 102507-71-1
Target:
Research Areas:
Tigemonam is an orally active monobactam antibiotic with a Ki of 0.86 μM against Enterobacter cloacae P99 β-lactamase and 50.8 μM against Escherichia coli TEM-1 β-lactamase. Tigemonam binds to penicillin-binding proteins 1a, 3, and 4, inhibits bacterial cell wall synthesis, and exhibits bactericidal activity against aerobic gram-negative bacteria including Enterobacteriaceae, Haemophilus influenzae, and Neisseria gonorrhoeae. Tigemonam resists hydrolysis by multiple β-lactamase enzymes, reduces bacterial load in systemic, pyelonephritic, lung, and thigh muscle infections in rodents, and shows minimal difference between minimum inhibitory and bactericidal concentrations. Tigemonam can be used for the research of gram-negative bacterial infections, acute pyelonephritis, lung infection, and thigh muscle infection [1] .
Cat. No.: HY-14879BR
CAS No.: 2938989-90-1
Synonyms: NXL-104 hydrate (Standard)
Research Areas:
Avibactam (sodium hydrate) (Standard) is the analytical standard of Avibactam (sodium hydrate). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1].
Cat. No.: HY-14879E
CAS No.: 1383814-68-3
Synonyms: NXL-104 sodium
Target:
Research Areas:
Ent-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of rel-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes [1] .
Cat. No.: HY-14879C
Synonyms: NXL-104 dihydrate
Target:
Research Areas:
Avibactam sodium (NXL-104) dihydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively [1].
Cat. No.: HY-14879R
CAS No.: 1192500-31-4
Synonyms: NXL-104 free acid (Standard)
Research Areas:
Avibactam (free acid) (Standard) is the analytical standard of Avibactam (free acid). This product is intended for research and analytical applications. Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1].
Cat. No.: HY-128049
CAS No.: 1212185-26-6
Target:
Research Areas:
ML121 is a selective and potent VIM-2 inhibitor with an IC50 of 54 nM and a Ki of 148 nM. ML121 shows inactive in IMP-1 and TEM-1 beta-lactamase assays. ML121 can potentiate the antibiotic activity of Imipenem (HY-B1369A) in VIM-2 transformed E.coli [1].
Cat. No.: HY-14879D
CAS No.: 396731-20-7
Synonyms: AVE1330A
Target:
Research Areas:
Ent-Avibactam sodium (AVE1330A) is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), ent-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of ent-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes [1].
Cat. No.: HY-RS02215
Target:
Research Areas:
CD248 Human Pre-designed siRNA Set A contains three designed siRNAs for CD248 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18990
Target:
Research Areas:
Cd248 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd248 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-105560
CAS No.: 41952-52-7
Target:
Research Areas:
Cefcanel is an orally active cephalosporin and antibacterial agent. Cefcanel inhibits growth of methicillin-susceptible Staphylococcus aureus, methicillin-susceptible Staphylococcus epidermidis, Haemophilus influenzae, Moraxella catarrhalis. Cefcanel acts as a substrate hydrolyzed by TEM-1, TEM-3, and Moraxella Bro-1 beta-lactamases [1].
Cat. No.: HY-P700831
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Endosialin; CD248; CD164L1; TEM1; CD164 sialomucin-like 1; CD164L1; CD248 molecule
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
