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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
UT-B inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "UT-B inhibitor" in MCE Product Catalog:
1
1 Cited Publications
Target:
연구분야:
UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
Cat. No.: HY-184585
Target:
연구분야:
UT-B-IN-2 is an orally active UT-B inhibitor, with an IC50 of 0.11 μM in mice and 0.054 μM in rats. UT-B-IN-2 induces diuretic effects in rats. UT-B-IN-2 can be used in the research of cardiovascular diseases and edema-related diseases .
Cat. No.: HY-131382
CAS No.: 332144-37-3
Target:
연구분야:
UTA1inh-C1 is a urea transporter (UT-A) inhibitor with IC50 of 4.2 μM .
Cat. No.: HY-116718
CAS No.: 892745-28-7
Target:
연구분야:
UTA1inh-D1 is a selective UT-A1 and UT-B urea transporter inhibitor with IC50 values of 3.8 μM and 15 μM, respectively. UTA1inh-D1 is promising for research of refractory edema, such as congestive heart failure and cirrhosis .
Cat. No.: HY-124107
CAS No.: 1251688-22-8
Target:
연구분야:
UTA1inh-A1 is a urea transporter (UT) inhibitor. UTA1inh-A1 has IC50 values of 3.3 μM and 16 μM for UT-A1 and UT-B. UTA1inh-A1 can be used in research related to urearetics .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
