892745-28-7
892745-28-7
Chemical Structure
UTA1inh-D1
- CAS No.: 892745-28-7
- Formula:C18H19N5O2S2
- Molecular Weight:401.50
IUPAC Name: 3-((2,5-dimethylphenyl)sulfonyl)-N-isopropylthieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine
InChIKey: TZKAXVMSVDWDPN-UHFFFAOYSA-N
SMILES: O=S(=O)(C=1N=NN2C1N=C(NC(C)C)C=3SC=CC32)C4=CC(=CC=C4C)C
Biological Activity: UTA1inh-D1 is a selective UT-A1 and UT-B urea transporter inhibitor with IC50 values of 3.8 μM and 15 μM, respectively. UTA1inh-D1 is promising for research of refractory edema, such as congestive heart failure and cirrhosis[1].
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UTA1inh-D1 | UTA1inh-D1 is a selective UT-A1 and UT-B urea transporter inhibitor with IC50 values of 3.8 μM and 15 μM, respectively. UTA1inh-D1 is promising for research of refractory edema, such as congestive heart failure and cirrhosis. | |||||||||||||||||||||
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References
Keywords
