3 Results for "

Wnt/Ca2+

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Wnt/Ca2+" in MCE Product Catalog:

11
Box5
Box5
0 Images
11 Cited Publications
Cat. No.: HY-123071
CAS No.: 1206604-29-6
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Cancer

Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma .
11
Box5 TFA
Box5 TFA
0 Images
11 Cited Publications
Cat. No.: HY-123071A
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Cancer

Box5 TFA is a potent Wnt5a antagonist. Box5 TFA inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 TFA inhibits cell migration. Box5 TFA has the potential for the research of melanoma .
IM-12 (GMP)
IM-12 (GMP)
0 Images
Cat. No.: HY-12292G
CAS No.: 1129669-05-1
IM-12 GMP is IM-12 (HY-12292) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IM-12 is an orally active anti-inflammatory agent that targets and inhibits the NF-κB and STAT3 signaling pathways. IM-12 activates the Wnt signaling pathway and promotes the nuclear translocation of β-catenin by inhibiting GSK3β, while also blocking the tyrosine kinase activity of p210BCR/ABL. IM-12 reduces the levels of IL-6, IL-17, NO, prostaglandin E2, iNOS and COX-2, and induces ER stress, Ca 2+ release, autophagy and apoptosis. IM-12 is heat-sensitive and does not induce autophagy in IM-resistant p210BCR/ABL T315I mutant cells. IM-12 is also a component of the 5iLA medium used for naive pluripotent stem cell research. IM-12 has been applied in studies related to carrageenan (HY-125474)-induced hind paw edema, TNBS-induced colitis, and acute and chronic myeloid leukemia .
Assay Types