10 Results for "

absolute configuration

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "absolute configuration" in MCE Product Catalog:

Cat. No.: HY-121125
CAS No.: 64274-28-8
Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .
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Cat. No.: HY-W098280
CAS No.: 26682-99-5
Research Areas:  

Others

Phenylglycine methyl ester is a chiral anisotropic reagent. Phenylglycine methyl ester can be used for absolute configuration determination of various chiral carboxylic acids .
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Cat. No.: HY-125949
CAS No.: 1445952-33-9
Kanshone H (compound 6) is a sesquiterpene compound isolated from the underground parts of spikenard .
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Cat. No.: HY-136926
CAS No.: 58591-23-4
Synonyms: FR-008I
Target:  

Fungal

Research Areas:  

Infection

Candicidin A3 (FR-008I) is an antifungal antibiotic with significant biological activity. Candicidin A3 can effectively inhibit the growth of fungi through its unique three-dimensional structure and seven-membered ring geometry. The absolute configuration of Candicidin A3 is a specific arrangement of multiple chiral centers, which may affect its biological activity and interaction with targets. Candicidin A3 can be used as a potential drug to inhibit fungal infections .
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Cat. No.: HY-N12964
CAS No.: 106941-27-9
4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .
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Cat. No.: HY-N9816
CAS No.: 393862-19-6
Plucheoside B (Compound 7b) aglycone is an aglycone of plucheoside B with an absolute configuration of 3R, 4R, and 9R that can be isolated from the leaves of Croton cascarilloides Räuschel .
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Cat. No.: HY-N19839
CAS No.: 141897-12-3
Synonyms: Stratioside II
Kiwiionoside (Stratioside II) is a glycoside compound found in kiwifruit. Kiwiionoside can be used as a drug intermediate .
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Cat. No.: HY-N18043
CAS No.: 103744-81-6
Rehmaglutin C is an iridoid lactone.Rehmaglutin C can be found in the dried root of Rehmannia glutinosa LiBosCH .
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Cat. No.: HY-19205B
CAS No.: 205654-37-1
(2S,5S)-CMI-392 is the absolute configuration of CMI-392 (HY-19205A). CMI-392 is an orally active dual 5-lipoxygenase inhibitor and platelet-activating factor receptor (PAFR) antagonist, with an IC50 of 10 nM for human PAF receptor and an IC50 of 100 nM for rat 5-lipoxygenase. CMI-392 blocks PAF receptor binding, inhibits leukotriene synthesis, attenuates PAF-induced hemoconcentration, and suppresses arachidonic acid- and TPA-induced ear swelling in mice. CMI-392 reduces inflammatory cell infiltration, decreases MPO levels, alleviates ocular inflammation, and improves dextran sulfate sodium-induced colitis. CMI-392 can be used in the research of inflammatory and immune-related diseases such as colitis and atopic dermatitis .
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Cat. No.: HY-N13729
CAS No.: 2376309-57-6
Stephalonine P is a hasubanan-type alkaloid anti-inflammatory agent with neuroprotective effects against neuroinflammation. Stephalonine P regulates post-ischemic inflammatory responses by inhibiting NO production in LPS-activated BV2 microglia (IC50=34.01 μM), thereby reducing microglial activation and neuronal damage. Stephalonine P can be isolated from the whole plant of Stephania japonica. Stephalonine P can be used in research on stroke and other neuroinflammation-related diseases .
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