127 Results for "

amide bonds

" in MedChemExpress (MCE) Product Catalog:
Products (127)

127 Results for "amide bonds" in MCE Product Catalog:

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14
14 Publications Verification
Cat. No.: HY-D0178
CAS No.: 25952-53-8
1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .
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2
2 Cited Publications
Cat. No.: HY-Y1168
CAS No.: 3945-69-5
Synonyms: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials .
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1 Cited Publications
Cat. No.: HY-112624I
CAS No.: 9004-54-0
Synonyms: Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
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Cat. No.: HY-W1048558A
Synonyms: mPEG2000-COOH
mPEG2000-CM (mPEG2000-COOH) is a carboxyl-terminated monomethoxy polyethylene glycol. mPEG2000-CM bears a reactive carboxyl group (-COOH) at its structural terminal site, which can form stable amide bonds with amino groups and ester bonds with hydroxyl groups. mPEG2000-CM binds to PCA-g-PCL copolymers via electrostatic interaction to form polyion complex micelles with a hydrophilic PEG surface, which enhances the stability of micelles in aqueous media. mPEG2000-CM can be used for drug delivery .
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Cat. No.: HY-112624K
CAS No.: 9004-54-0
Synonyms: Dextran 5; Dextran D5; Dextran T5(MW 4500-5500)
Dextran T5 (MW 5,000) is a sulfated polysaccharide anti-apoptotic and autophagic agent. Dextran T5 (MW 5,000) has sulfated groups and interacts with cell membranes by mimicking endogenous glycosaminoglycans, inhibiting the mitochondrial apoptotic pathway and delaying DNA fragmentation to exert anti-apoptotic activity. Dextran T5 (MW 5,000) also promotes the conversion of LC3-I to LC3-II and the formation of autophagosomes to activate the autophagic pathway. Dextran T5 (MW 5,000) can prolong the survival cycle of CHO cells and increase the production of recombinant erythropoietin (EPO). The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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Cat. No.: HY-112624H
CAS No.: 9004-54-0
Synonyms: Dextran 2; Dextran D2; Dextran T2(MW 1600-2400)
Dextran T2 (Dextran 2; Dextran T2(MW 1600-2400)) is a natural high molecular weight polysaccharide, the glycosidic bonds in its structure can be recognized by endo-dextranase and exo-dextranase. Dextran T2 (MW 2,000) breaks the glycosidic bonds in the enzymatic hydrolysis mechanism, releasing products such as D-glucose, Isomaltose (IM2), and Isomaltotriose (IM3). Dextran T2 (MW 2,000) can be used as a model substrate to characterize the catalytic properties of dextranase (such as optimal pH, temperature and product specificity), and to study enzymatic mechanism research and polysaccharide degradation pathways in glycobiology. The Dextran series of compounds are also a natural polysaccharide drug carrier, which can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong drug half-life, increase local concentration and reduce immune clearance activity .
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Cat. No.: HY-W437745
CAS No.: 80750-24-9
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
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Cat. No.: HY-D1085
CAS No.: 216309-02-3
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
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Cat. No.: HY-W451406C
CAS No.: 956496-54-1
Research Areas:  

Others

NH2-PEG2000-NH2 is a PEG (MW = 2000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
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Cat. No.: HY-157745
CAS No.: 92451-01-9
Purity:  ≥98.0%
Synonyms: mPEG40000-SC; mPEG40000-Succinimidyl ester
Research Areas:  

Others

m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .
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Cat. No.: HY-W243460
CAS No.: 39208-15-6
Research Areas:  

Others

EDTA copper (II) disodium salt, 97% is a negatively charged copper (II)-ethylenediaminetetraacetic acid chelate and also an adsorption substrate. EDTA copper (II) disodium salt, 97% forms amide bonds with chitosan amino groups in weakly acidic (pH 3-5) solutions, while it forms the CuEDTA (OH) 3− hydroxyl complex in strongly alkaline (pH > 12) solutions. EDTA copper (II) disodium salt, 97% can be adsorbed onto granular activated carbon, with electrostatic interactions dominating its pH-dependent adsorption behavior. EDTA copper (II) disodium salt, 97% can be used to eliminate the inhibition of enzyme-catalyzed reactions caused by trace heavy metals .
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Cat. No.: HY-W1048525
Synonyms: 8-Arm PEG5000-Amine
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-W1048843A
CAS No.: 169501-65-9
Synonyms: 4-Arm PEG5000-amine
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-W190877
CAS No.: 1260092-48-5
Synonyms: SH-PEG1-COOH
Thiol-PEG1-acid (SH-PEG1-COOH) is a PEG derivative consisting of a thiol (-SH), 1 PEG unit, and a carboxyl (-COOH). The thiol is a highly reactive chemical group that can react specifically with a variety of molecules to form stable covalent bonds. The carboxyl group can easily form stable amide bonds with amino groups, and can also form ester bonds with hydroxyl groups.
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Cat. No.: HY-E70137
Target:  

Drug Intermediate

Research Areas:  

Others

AMG 118 Immobilized cephalosporin C acylase is an enzyme that catalyzes in immobilized form and is generally used in industrial catalytic production of the important pharmaceutical intermediate 7-aminocephalosporanic acid (7-ACA). It contains CPC acylase, a highly specialized beta-lactam acylase or peptidase that cleaves the amide bonds between beta-lactams .
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Cat. No.: HY-W1048843B
CAS No.: 169501-65-9
Synonyms: 4-Arm PEG10000-amine
4-Arm PEG10000-NH2 (4-Arm PEG10000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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Cat. No.: HY-151647
CAS No.: 1240801-10-8
Research Areas:  

Others

3-Azidopropanoic acid-PFP ester is an azidopropanoic acid linker that contains an activated PFP ester. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to form triazole linkages. The activated PFP ester can react with amine groups to form stable amide bonds . 3-Azidopropanoic acid-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-W099632
CAS No.: 25354-97-6
2-Hexyldecanoic acid is a lipid containing one carboxylic acid group and two non-polar tails. In the presence of EDC, HATU and DCC, carboxylic acid groups can undergo continuous amide coupling reactions with amine-containing biomolecules to form stable amide bonds. 2-Hexyldecanoic acid can be used as an aerolysin inhibitor to prevent bacterial pathogens. 2-Hexyldecanoic acid can cause contact dermatitis .
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Cat. No.: HY-W011118
CAS No.: 23911-26-4
Research Areas:  

Cancer

DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.
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