DMTMM
Based on 2 publication(s) in Google Scholar
DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 3945-69-5
- Formula: C10H17ClN4O3
- Molecular Weight:276.72
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DMTMM
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Biological Activity
NorHA hydrogels synthesized by DMTMM can promote cell (hMSCs and bCHs) spreading[2].
CLP-PEG-MPC hydrogels prepared by DMTMM support the proliferation of human corneal epithelial cells (HCEC)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3945-69-5
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Appearance Solid
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Molecular Weight 276.72
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Formula C10H17ClN4O3
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Color White to off-white
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SMILES
C[N+]1(C2=NC(OC)=NC(OC)=N2)CCOCC1.[Cl-]
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Synonyms
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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J Am Chem Soc
Structural Mass-Spectrometric Description of Immune Complexes in Vaccine-Induced Immune Thrombocytopenia and Thrombosis. [Abstract]2026 Mar 24. PMID: 41875409 -
Solvent & Solubility
DMSO : 50 mg/mL (180.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (294 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
[3]. Simpson FC, et al. Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs. Commun Biol. 2021 May 21;4(1):608. [Content Brief]
[4]. Labre F, et al. DMTMM-mediated amidation of alginate oligosaccharides aimed at modulating their interaction with proteins. Carbohydr Polym. 2018 Mar 15;184:427-434. [Content Brief]
[5]. Magalhães MV, et al. In situ crosslinkable multi-functional and cell-responsive alginate 3D matrix via thiol-maleimide click chemistry. Carbohydr Polym. 2024 Aug 1;337:122144. [Content Brief]
[6]. Jo G, et al. Tumor Targeting with Methotrexate-Conjugated Zwitterionic Near-Infrared Fluorophore for Precise Photothermal Therapy. Int J Mol Sci. 2022 Nov 16;23(22):14127. [Content Brief]
[7]. Morieux P, et al. Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives. Bioorg Med Chem. 2008 Oct 1;16(19):8968-75. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6137 mL | 18.0685 mL | 36.1371 mL | 90.3427 mL |
| 5 mM | 0.7227 mL | 3.6137 mL | 7.2274 mL | 18.0685 mL | |
| 10 mM | 0.3614 mL | 1.8069 mL | 3.6137 mL | 9.0343 mL | |
| 15 mM | 0.2409 mL | 1.2046 mL | 2.4091 mL | 6.0228 mL | |
| 20 mM | 0.1807 mL | 0.9034 mL | 1.8069 mL | 4.5171 mL | |
| 25 mM | 0.1445 mL | 0.7227 mL | 1.4455 mL | 3.6137 mL | |
| 30 mM | 0.1205 mL | 0.6023 mL | 1.2046 mL | 3.0114 mL | |
| 40 mM | 0.0903 mL | 0.4517 mL | 0.9034 mL | 2.2586 mL | |
| 50 mM | 0.0723 mL | 0.3614 mL | 0.7227 mL | 1.8069 mL | |
| 60 mM | 0.0602 mL | 0.3011 mL | 0.6023 mL | 1.5057 mL | |
| 80 mM | 0.0452 mL | 0.2259 mL | 0.4517 mL | 1.1293 mL | |
| 100 mM | 0.0361 mL | 0.1807 mL | 0.3614 mL | 0.9034 mL |
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