3945-69-5
3945-69-5
Chemical Structure
DMTMM
Synonym(s): 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
- CAS 番号: 3945-69-5
- Formula:C10H17ClN4O3
- Molecular Weight:276.72
IUPAC Name: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride
InChIKey: BMTZEAOGFDXDAD-UHFFFAOYSA-M
SMILES: C[N+]1(C2=NC(OC)=NC(OC)=N2)CCOCC1.[Cl-]
Biological Activity: DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials[1][2][3][4][5][6][7][8].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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DMTMM | 99.53% | DMTMM (4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methylmorpholinium chloride) is a coupling agent. DMTMM can activate carboxyl groups and promote the formation of amide bonds. DMTMM plays an important role in promoting the chemical modification of biomacromolecules such as polysaccharides and proteins. DMTMM can be used for research of tissue engineering, breast cancer, corneal regeneration, and biomaterials. | ||||||||||||||||||||
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GAL-021 | 99.93% | GAL-021 is a potent BKCa-channel blocker. GAL-021 inhibits KCa1.1 in GH3 cells. GAL-021 is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 increases minute ventilation in rats and non-human primates. | ||||||||||||||||||||
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Trimelamol | Trimelamol (CB10-375; NSC283162) is a highly efficient acid-catalyzed DNA interstrand crosslinker with low neurotoxicity due to its limited BBB penetration. Trimelamol exhibits anti-tumor activity and overcomes platinum resistance. Trimelamol is investigated for lung and ovarian cancer research. | |||||||||||||||||||||
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CB-7646 | CB-7646, a Trimelamol (HY-106768) analogue, is an anti-tumour agent. CB-7646 can be used for research of ovarian cancer and breast cancer. | |||||||||||||||||||||
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UCB-11056 | UCB-11056 is a modulator of cyclic AMP generation. UCB-11056 can rapidly increase cyclic AMP levels in the rat brain in vivo and potentiate stimulated cyclic AMP formation in vitro. UCB-11056 does not stimulate cAMP formation on its own. UCB-11056 is a potential nootropic drug. | |||||||||||||||||||||
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CXCL12 ligand 1 | CXCL12 ligand 1 is the first ligand of the sY12-binding pocket on chemokine CXCL12. | |||||||||||||||||||||
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Simeton-acetic acid | Simeton-acetic acid is an immunizing hapten that can be coupled with bovine serum albumin. Simeton-acetic acid-BSA can produce PcAbs obtained with titer 1.0×103. | |||||||||||||||||||||
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Altretamine hydrochloride | Altretamine hydrochloride is an alkylating antineoplastic agent. | |||||||||||||||||||||
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Terbumeton | Terbumeton is a methoxytriazine herbicide, which inhibits sensitive weeds' growth through inhibition of photosynthesis. | |||||||||||||||||||||
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mTOR ligand 1 | 99.68% | mTOR ligand 1 (compound T2) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). mTOR ligand 1 can serve as an active control for MHY1485 (HY-B0795, the target protein ligand of PD-M6 (HY-176166). | ||||||||||||||||||||
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Prometon-d3 | Prometon-d3 is the deuterium labeled Prometon. | |||||||||||||||||||||
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References
- [1]. Bergmeyer H U, et al. Biochemical reagents[M]//Methods of Enzymatic Analysis. Academic Press, 1965: 967-1037.
- [2]. Plaster E M, et al. DMTMM-mediated synthesis of norbornene-modified hyaluronic acid polymers to probe cell-hydrogel interactions. Carbohydrate Polymer Technologies and Applications, 2023, 6: 100360.
- [3]. Simpson FC, et al. Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs. Commun Biol. 2021 May 21;4(1):608. [Content Brief]
- [4]. Labre F, et al. DMTMM-mediated amidation of alginate oligosaccharides aimed at modulating their interaction with proteins. Carbohydr Polym. 2018 Mar 15;184:427-434. [Content Brief]
- [5]. Magalhães MV, et al. In situ crosslinkable multi-functional and cell-responsive alginate 3D matrix via thiol-maleimide click chemistry. Carbohydr Polym. 2024 Aug 1;337:122144. [Content Brief]
- [6]. Jo G, et al. Tumor Targeting with Methotrexate-Conjugated Zwitterionic Near-Infrared Fluorophore for Precise Photothermal Therapy. Int J Mol Sci. 2022 Nov 16;23(22):14127. [Content Brief]
- [7]. Morieux P, et al. Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives. Bioorg Med Chem. 2008 Oct 1;16(19):8968-75. [Content Brief]
- [8]. Hyun H, et al. Engineered beta-cyclodextrin-based carrier for targeted doxorubicin delivery in breast cancer therapy in vivo. Journal of Industrial and Engineering Chemistry, 2019, 70: 145-151.
