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arsenic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Arenavirus (1) Biochemical Assay Reagents (2) Cadherin (1) Dengue Virus (1) Drug Intermediate (1) Endogenous Metabolite (1) Epigenetic Reader Domain (1) HIV (2) Isotope-Labeled Compounds (1) Mitochondrial Metabolism (2) nAChR (1) Parasite (4) Ras (1) Reactive Oxygen Species (ROS) (2) Reference Standards (1) SOD (1) VSV (1)
By Research Areas:	Cancer (9) Infection (8) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

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Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1285

Dimercaprol 1 Publications Verification 2,3-Dimercapto-1-propanol; Dithioglycerol	HIV	Infection
Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning .

HY-13963

ZCL278 3 Publications Verification	Ras Dengue Virus VSV Arenavirus	Infection Neurological Disease Metabolic Disease Cancer
ZCL278 is a selective Cdc42 inhibitor with K_ds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 is able to disrupt the Cdc42-ITSN interaction as well as GTP/GDP binding. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used for the studies of arsenic neurotoxicity and HER2-positive gastric cancer (GC) .

HY-138502A

Melarsomine dihydrochloride	Parasite	Infection
Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections .

HY-119594

Melarsoprol	Parasite Apoptosis	Infection Neurological Disease Inflammation/Immunology Cancer
Melarsoprol, a melaminophenylarsine-type trivalent organic arsenical, is an important agent for African trypanosomiasis. Melarsoprol inhibits the growth of lymphoid leukemic cell by inducing apoptosis. Melarsoprol crosses the blood-brain barrier .

HY-16386

PENAO	Mitochondrial Metabolism	Cancer
PENAO is a potent tumour cell mitochondrial toxin. PENAO inactivates tumor cell mitochondria by targeting inner-membrane adenine nucleotide transferase .

HY-W741573

*N-Biotinyl p-aminophenyl arsenic* acid**	nAChR	Neurological Disease
N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that can bind to both streptavidin and dithiols. N-Biotinyl p-aminophenyl arsenic acid decreases the Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors (IC₅₀ is 10-300 nM), and protects the receptor from irreversible alkylation by bromoacetylcholine .

HY-14943

Darinaparsin ZIO-101; S-Dimethylarsino-glutathione	Apoptosis	Cancer
Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects .

HY-16386A

PENAO TFA	Mitochondrial Metabolism	Cancer
PENAO TFA is the trifluoroacetic acid of PENAO (HY-16386). PENAO is a potent tumour cell mitochondrial toxin. PENAO inactivates tumor cell mitochondria by targeting inner-membrane adenine nucleotide transferase .

HY-138502

Melarsomine	Parasite	Infection
Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections .

HY-B1285R

Dimercaprol (Standard) 2,3-Dimercapto-1-propanol (Standard); Dithioglycerol (Standard)	Reference Standards HIV	Infection
Dimercaprol (Standard) is the analytical standard of Dimercaprol. This product is intended for research and analytical applications. Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning .

HY-113949

Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside	Drug Intermediate	Others
Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside is a furanose derivative. Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside serves as an important intermediate for the synthesis of compounds such as arsenic-containing ribosides .

HY-W017224

Sodium butane-1-sulfonate Sodium 1-butanesulfonate	Biochemical Assay Reagents	Others
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) is an ion-pair reagent. Sodium butane-1-sulfonate is often used in combination with tetramethylammonium hydroxide, malonic acid, etc. in reversed-phase ion-pair chromatography, and can improve the separation efficiency of species of elements such as arsenic and selenium .

HY-Y0443

Triphenylarsine Triphenyl arsenic	Biochemical Assay Reagents	Others
Triphenylarsine (Triphenyl arsenic) is a kind of biological materials or organic compounds that are widely used in life science research.

HY-N16399

Black tea extract	Reactive Oxygen Species (ROS) Cadherin	Cancer
Black tea extract is the extract of Black tea. Black tea extract prevents inorganic arsenic (iAs) induced ROS generation, inhibiting uncontrolled proliferation, epithelial to mesenchymal transition (EMT) and metastasis in HaCaT cells. Black tea extract has an anti-fibrotic activity. Black tea extract can be used for skin cancers research .

HY-145909

BRD4 Inhibitor-17	Epigenetic Reader Domain	Cancer
BRD4 Inhibitor-17 (Compound 5i) is a potent inhibitor of BRD4 with an IC₅₀ of 0.33 μM. BRD4 Inhibitor-17 plays crucial role in regulating transcription of inflammatory, proliferation and cell cycle genes. BRD4 Inhibitor-17 serves as potential antidotes for arsenicals .

HY-122461

Glycobiarsol	Parasite	Infection
Glycobiarsol is an organic arsenical compound, which can be used as an amoebicidal agent. Glycobiarsol exhibits toxicity and side effects .

HY-177995

MiADMSA Monoisoamyl meso-2,3-dimercaptosuccinic acid	Reactive Oxygen Species (ROS) SOD	Neurological Disease Cancer
MiADMSA (Monoisoamyl meso-2,3-dimercaptosuccinic acid) is an orally active thiol chelator that can effectively remove heavy metals such as arsenic and lead from the body of animals. Arsenic binds with two vicinal sulfhydryl groups available in MiADMSA leading to marked reduction in body arsenic burden and also marked reduction in various oxidative stress parameters and antioxidant enzymes like-ROS, nitrite, TBARS, GSH, SOD and catalase. MiADMSA attenuates urinary bladder carcinogenesis, protects against oxidative stress, ameliorates copper-induced histopathology, reverses neurotoxicity, and is safe in animals. MiADMSA can be used in studies of bladder cancer, arsenic, and lead-induced developmental neurotoxicity .

HY-13963S

ZCL278-13C	Isotope-Labeled Compounds Endogenous Metabolite	Infection Cancer
ZCL278- ¹³C is a ¹³C-labeled version of ZCL278 (HY-13963). ZCL278 is a selective Cdc42 inhibitor with K_ds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 can disrupt the interaction between Cdc42 and ITSN, and also inhibit the binding of GTP and GDP. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used in the research of arsenic neurotoxicity and HER2-positive gastric cancer (GC) ^[1][2][3][4].

Cat. No.	Product Name	Type

HY-W017224

Sodium butane-1-sulfonate Sodium 1-butanesulfonate	Biochemical Assay Reagents
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) is an ion-pair reagent. Sodium butane-1-sulfonate is often used in combination with tetramethylammonium hydroxide, malonic acid, etc. in reversed-phase ion-pair chromatography, and can improve the separation efficiency of species of elements such as arsenic and selenium .

HY-Y0443

Triphenylarsine Triphenyl arsenic	Biochemical Assay Reagents
Triphenylarsine (Triphenyl arsenic) is a kind of biological materials or organic compounds that are widely used in life science research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16399

Black tea extract	Natural Products Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Reactive Oxygen Species (ROS) Cadherin
Black tea extract is the extract of Black tea. Black tea extract prevents inorganic arsenic (iAs) induced ROS generation, inhibiting uncontrolled proliferation, epithelial to mesenchymal transition (EMT) and metastasis in HaCaT cells. Black tea extract has an anti-fibrotic activity. Black tea extract can be used for skin cancers research .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71298

	Serpin H1 Protein, Human (HEK293, His) Serpin H1; 47 kDa Heat Shock Protein; arsenic-Transactivated Protein 3; AsTP3; Cell Proliferation-Inducing Gene 14 Protein; Collagen-Binding Protein; Colligin; Rheumatoid Arthritis-Related Antigen RA-A47; SERPINH1; CBP1; CBP2; HSP47; SERPINH2	Human	HEK293
	Serpin H1 protein exhibits a specific affinity for collagen, indicating its role as a chaperone in the biosynthetic pathway of collagen. This suggests its potential contribution to collagen synthesis, emphasizing its importance in maintaining tissue integrity and modulating cellular responses related to collagen metabolism. Serpin H1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin H1 protein, expressed by HEK293 , with C-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-13963S

ZCL278-13C
ZCL278- ¹³C is a ¹³C-labeled version of ZCL278 (HY-13963). ZCL278 is a selective Cdc42 inhibitor with K_ds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 can disrupt the interaction between Cdc42 and ITSN, and also inhibit the binding of GTP and GDP. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used in the research of arsenic neurotoxicity and HER2-positive gastric cancer (GC) ^[1][2][3][4].

ZCL278-13C

ZCL278- ¹³C is a ¹³C-labeled version of ZCL278 (HY-13963). ZCL278 is a selective Cdc42 inhibitor with K_ds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 can disrupt the interaction between Cdc42 and ITSN, and also inhibit the binding of GTP and GDP. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used in the research of arsenic neurotoxicity and HER2-positive gastric cancer (GC) ^[1][2][3][4].

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