BRD4 Inhibitor-17
BRD4 Inhibitor-17 (Compound 5i) is a potent inhibitor of BRD4 with an IC50 of 0.33 μM. BRD4 Inhibitor-17 plays crucial role in regulating transcription of inflammatory, proliferation and cell cycle genes. BRD4 Inhibitor-17 serves as potential antidotes for arsenicals.
For research use only. We do not sell to patients.
- CAS No.: 2835555-10-5
- Formula: C16H16FN3O3S
- Molecular Weight:349.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | IC50 |
0.83 μM
Compound: 5i
|
Antiinflammatory activity against human THP-1 cells assessed as inhibition of LPS-induced IL-6 production incubated for 18 hrs by ELISA
Antiinflammatory activity against human THP-1 cells assessed as inhibition of LPS-induced IL-6 production incubated for 18 hrs by ELISA
|
[PMID: 35318165] |
Chemical Information
-
CAS No. 2835555-10-5
-
Molecular Weight 349.38
-
Formula C16H16FN3O3S
-
SMILES
CC1=CC(S(=O)(NC2=CC3=C(NC(N(C3)C)=O)C=C2)=O)=CC=C1F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4 Inhibitor-17 Related Classifications
HY-145909 Related Classifications
Powered by Bioz