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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
aspartyl
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "aspartyl" in MCE Product Catalog:
6
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Research Areas:
L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3 nM, respectively. L-685458 can be used for the research of alzheimer’s disease (AD) and cancers .
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4 Cited Publications
Cat. No.: HY-16477
CAS No.: 220201-34-3
Synonyms: ME2906; Mono-L-aspartyl chlorin e6; NPe6
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Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .
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Cat. No.: HY-E70196
CAS No.: 55576-49-3
Synonyms: Asp-N
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Endoproteinase Asp-N (MS grade) is a metalloprotease that can specifically cleave the N-terminal side of aspartyl and cysteic acid residues .
Synonyms: Adenylosuccinate; aspartyl adenylate
Category:
Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields
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Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme.
Synonyms: L-β-aspartyl-L-aspartic acid
Category:
Liliaceae Ketones, Aldehydes, Acids Other Diseases Plants Disease Research Fields Asparagus officinalis L.
Target:
Cat. No.: HY-23093
CAS No.: 13433-09-5
Research Areas:
L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
Cat. No.: HY-164410
CAS No.: 1585217-40-8
MO-I-1100 is an inhibitor of ASPH (Aspartyl-(Asparaginyl)-β-hydroxylase) enzymatic activity. MO-I-1100 suppresses HCC cell migration, invasion and anchorage independent growth. MO-I-1100 shows antitumor effects through inhibiting Notch signaling cascade in HCC .
Synonyms: DA-DKP
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Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy .
Cat. No.: HY-127137A
Purity: ≥98.0%
Synonyms: Adenylosuccinate tetraammonium; aspartyl adenylate tetraammonium
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Adenylosuccinic acid tetraammonium (Adenylosuccinate; Aspartyl adenylate) is an orally active purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid tetraammonium can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid tetraammonium has the potential for the study of duchenne muscular dystrophy(DMD) .
Cat. No.: HY-P4727
CAS No.: 82602-88-8
Synonyms: DSIP-isoD
Cat. No.: HY-P4285
CAS No.: 13110-25-3
Cat. No.: HY-142031
CAS No.: 519034-65-2
4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor. 4-Piperidinecarboxamide is a promising anti-tuberculosis (TB) agent .
Cat. No.: HY-23093R
CAS No.: 13433-09-5
Research Areas:
L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
Cat. No.: HY-W592871R
CAS No.: 765-01-5
Synonyms: 10-HDA (Standard); Queen Bee Acid (Standard)
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Target:
Cat. No.: HY-D1532
CAS No.: 263718-22-5
Cat. No.: HY-178374
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BACE-1/Mpro-IN-1 is a high brain-penetrant BACE-1 (IC50 = 0.26 μM) and SARS-CoV-2 Mpro (IC50 = 0.91 μM) dual inhibitor. BACE-1/Mpro-IN-1 binds to the aspartyl protease and cysteine protease as a mixed-type inhibitor. BACE-1/Mpro-IN-1 exhibits the most favorable docking score and a strong interaction profile. BACE-1/Mpro-IN-1 can be used for the study of COVID-19 exacerbated Neuroinflammation and Alzheimer’s disease .
Cat. No.: HY-131280R
CAS No.: 676129-92-3
Target:
Research Areas:
L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
