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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
cell communication
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "cell communication" in MCE Product Catalog:
3
Research Areas:
Irsogladine (Dicloguamine) is an orally active gastric mucosal protective agent. Irsogladine inhibits breast cancer recurrence and lung metastasis in nude mice . Irsogladine inhibits the transcriptional activities of NF-κB and AP-1, suppresses the activities of PDE and PDE4 to elevate intracellular cAMP levels, and activates TRPV1 and KATP channels. Irsogladine enhances iNOS expression, NO production, and the activation of cAMP-responsive elements. Irsogladine inhibits the development and progression of intestinal polyps in Apc-mutant mice. Irsogladine alleviates oxidative stress, increases gastric mucosal blood flow, and stimulates the production of endogenous prostaglandins. Irsogladine promotes insulin secretion in MIN6 cells. Irsogladine inhibits tumor angiogenesis, cancer cell proliferation, and the production of proinflammatory cytokines. Irsogladine exerts protective effects on astrocytes in ethanol/hydrochloric acid-induced gastric ulcers in mice. Irsogladine prevents colitis in IL-10 gene-deficient mice by reducing the production of IL-12 and IL-23. Irsogladine upregulates gap junction intercellular communication in pancreatic cancer cells via the PKA pathway. Irsogladine is applicable to research related to breast cancer, intestinal polyposis, gastric ulcer, spontaneous colitis, glioma, liver cancer, and pancreatic cancer [5][6] .
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Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation .
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1 Cited Publications
Cat. No.: HY-W123005
CAS No.: 58537-94-3
Target:
Research Areas:
Dimethyl pimelimidate dihydrochloride is a bifunctional imidoester protein-protein crosslinker used in chromatin immunoprecipitation (ChIP) assays .
Synonyms: C10-HSL
Category:
Cat. No.: HY-D0830
CAS No.: 1170856-93-5
Synonyms: Fluorexon tetraethyl ester
Cat. No.: HY-W248583
CAS No.: 157410-23-6
Synonyms: PM650
Cat. No.: HY-Y0248AR
CAS No.: 4602-84-0
Cat. No.: HY-D1777
CAS No.: 137829-80-2
Synonyms: PM605
Cat. No.: HY-136409R
CAS No.: 177315-87-6
Synonyms: C10-HSL (Standard)
Category:
Cat. No.: HY-W248118
CAS No.: 121461-69-6
Synonyms: PM556
N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats .
Cat. No.: HY-133684R
CAS No.: 202284-87-5
Target:
Research Areas:
N-Tetradecanoyl-L-homoserine lactone (Standard) is the analytical standard of N-Tetradecanoyl-L-homoserine lactone (HY-133684). This product is intended for research and analytical applications. N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats.
Cat. No.: HY-133685S
CAS No.: 2705226-73-7
Synonyms: C6-HSL-d3
Cat. No.: HY-P11197
CAS No.: 895547-36-1
Target:
Research Areas:
Cat. No.: HY-106225R
CAS No.: 355151-12-1
Synonyms: ZP123 (Standard)
Research Areas:
Rotigaptide (Standard) is the analytical standard of Rotigaptide. This product is intended for research and analytical applications. Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically?atrial fibrillation .
Cat. No.: HY-115393A
CAS No.: 177158-20-2
N-Heptanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acyl-homoserine lactones (AHL) can regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria.
Cat. No.: HY-P10504
Synonyms: CEP1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
