7 Results for "

corepressor peptide

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "corepressor peptide" in MCE Product Catalog:

Cat. No.: HY-132205
CAS No.: 2735803-28-6
Purity:  99.18%
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease

DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM) .
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Cat. No.: HY-112247
CAS No.: 2088135-12-8
Purity:  99.89%
SR 16832 is a dual-site covalent, orthosteric and allosteric PPARγ antagonist. SR 16832 activates the TGF-β signaling pathway and upregulates the expression of Vimentin and Fibronectin (Fibronectin). SR 16832 is toxic to bronchial epithelium. SR 16832 can be used in research related to type 2 diabetes and pulmonary fibrosis .
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Cat. No.: HY-143201
CAS No.: 2735803-20-8
Purity:  99.34%
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease

DS20362725 is an estrogen-related receptor α (ERRα) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.6 μM. DS20362725 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM) .
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Cat. No.: HY-P10543
CAS No.: 857026-08-5
Target:  

BCL6

Research Areas:  

Cancer

SMRT peptide is one of the co-repressors of BCL6 BTB domain interaction. SMRT peptide binds to the BTB domain of BCL6 and enhances the transcriptional repression function of BCL6. SMRT peptide can be used to study protein-protein interactions .
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Cat. No.: HY-P10488
CAS No.: 2116533-34-5
Target:  

Wnt Peptides

Research Areas:  

Cancer

cycFWRPW is a peptide inhibitor of TLE1. TLE1 is an oncogenic transcriptional co‐repressor that exerts its repressive effects through binding of transcription factors, and inhibits Wnt signaling .
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Cat. No.: HY-161394
Research Areas:  

Cancer

SPRT is a short peptide of RB transcriptional corepressor 1 (RB), serving as a fragment of RB-CO-PEG5-C2-CO-VH032 (HY-161393) for the synthesis of PROTAC .
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Cat. No.: HY-182449
CAS No.: 2647503-59-9
Target:  

Bcl-2 Family

Research Areas:  

Cancer

CCT365386 is a BCL6 inhibitor. CCT365386 serves as an optimized lead compound for cell-active BCL6 degraders (including CCT369260 (HY-129188)). CCT365386 can be used in the research of B-cell lymphoma .
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