2735803-28-6
2735803-28-6
Chemical Structure
DS45500853
- CAS 番号: 2735803-28-6
- Formula:C18H20O3
- Molecular Weight:284.35
IUPAC Name: 1-(4-(3-(tert-butyl)-4-hydroxyphenoxy)phenyl)ethan-1-one
InChIKey: WSVZSZVSZTYTCC-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(OC2=CC=C(O)C(C(C)(C)C)=C2)C=C1)=O
Biological Activity: DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM)[1].
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DS45500853 | 99.18% | DS45500853 is an estrogen-related receptor α (ERRα) agonist. DS45500853 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.80 μM. DS45500853 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM). | ||||||||||||||||||||
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