12 Results for "

furocoumarin

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "furocoumarin" in MCE Product Catalog:

2
Xanthotoxol
Xanthotoxol
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2 Cited Publications
Cat. No.: HY-30152
CAS No.: 2009-24-7
Synonyms: 8-Hydroxypsoralen
Category:  

other families Monophenols Coumarins Phenols Phenylpropanoids Plants Endogenous metabolite

Target:  

5-HT Receptor Reactive Oxygen Species (ROS) Endogenous Metabolite

Xanthotoxol (8-Hydroxypsoralen) It is a kind of fragrant bean substance, and it is a CYP450 inhibitor. Xanthotoxol has anti-inflammatory, anti-inflammatory, and 5-HT antagonistic and protective effects. Xanthotoxol inhibited CYP3A4 sum CYP1A2 IC50s separation 7.43 μM sum 27.82 μM. Xanthotoxol can pass through MAPK and NF-κB, inhibiting inflammation.
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1
5-Hydroxy-8-methoxypsoralen
5-Hydroxy-8-methoxypsoralen
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1 Cited Publications
Cat. No.: HY-134039
CAS No.: 7471-73-0
Purity:  99.82%
Synonyms: 5-Hydroxyxanthotoxin
Category:  

Saussurea medusa Maxim. Monophenols Coumarins Phenols Phenylpropanoids Plants Umbelliferae Disease Research Fields Inflammation/Immunology

Target:  

Drug Metabolite

5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight .
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Phellopterin
Phellopterin
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Cat. No.: HY-N2110
CAS No.: 2543-94-4
Category:  

Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Inflammation/Immunology

Target:  

Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR) HIV

Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus .
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(-)-Heraclenol
(-)-Heraclenol
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Cat. No.: HY-N0944
CAS No.: 139079-42-8
Category:  

Natural Products other families Plants Disease Research Fields Cancer

Target:  

Others

(-)-Heraclenol is a derivative of furocoumarin isolated from Ducrosia anethifolia. (-)-Heraclenol shows antiproliferative and cytotoxic activities on cancer cell lines .
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Methoxsalen-d3
Methoxsalen-d3
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Cat. No.: HY-30151S
CAS No.: 80386-99-8
Synonyms: 8-Methoxypsoralen-d3; Xanthotoxin-d3; 8-MOP-d3
Methoxsalen-d3 is the deuterium labeled Methoxsalen[1]. Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[2].
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7-Hydroxy-5-methoxycoumarin
7-Hydroxy-5-methoxycoumarin
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Cat. No.: HY-N7179
CAS No.: 3067-10-5
Category:  

Coumarins Phenylpropanoids Plants Convolvulaceae Ipomoea batatas (Linn.) Lamarck

Target:  

Others

7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .
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Phellopterin (Standard)
Phellopterin (Standard)
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Cat. No.: HY-N2110R
CAS No.: 2543-94-4
Category:  

Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt.

Target:  

Reference Standards Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR) HIV

Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus.
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4,5'-Dimethylangelicin-NHS
4,5'-Dimethylangelicin-NHS
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Cat. No.: HY-150015
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .
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Gosferol
Gosferol
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Cat. No.: HY-N9523
CAS No.: 37551-62-5
Category:  

Euryops arabicus Steud. ex Jaub. & Spach Other Diseases Rutaceae Murraya koenigii (L.) Spreng Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields

Target:  

Others

Gosferol is a furocoumarin from the roots of Murraya koenigii .
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(-)-Oxypeucedanin hydrate
(-)-Oxypeucedanin hydrate
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Cat. No.: HY-N2254
CAS No.: 133164-11-1
Synonyms: (-)-Prangol
Category:  

other families Coumarins Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

Others

(-)-Oxypeucedanin hydrate ((-)-Prangol) is a derivative of furocoumarin isolated from Ducrosia anethifolia .
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Xanthotoxol (Standard)
Xanthotoxol (Standard)
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Cat. No.: HY-30152R
CAS No.: 2009-24-7
Synonyms: 8-Hydroxypsoralen (Standard)
Category:  

other families Monophenols Coumarins Phenols Phenylpropanoids Plants Endogenous metabolite

Target:  

Reference Standards 5-HT Receptor Reactive Oxygen Species (ROS) Endogenous Metabolite

Xanthotoxol (Standard) is the analytical standard of Xanthotoxol. This product is intended for research and analytical applications. Xanthotoxol (8-Hydroxypsoralen) It is a kind of fragrant bean substance, and it is a CYP450 inhibitor. Xanthotoxol has anti-inflammatory, anti-inflammatory, and 5-HT antagonistic and protective effects. Xanthotoxol inhibited CYP3A4 sum CYP1A2 IC50s separation 7.43 μM sum 27.82 μM. Xanthotoxol can pass through MAPK and NF-κB, inhibiting inflammation .
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Oroselone
Oroselone
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Cat. No.: HY-183394
CAS No.: 1760-27-6
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Oroselone is an angelicin-type furanocoumarin found in Prangos pabularia and Cachrys pungens, with weak antioxidant activity. Oroselone acts as an inhibitor of lipid peroxidation and a DPPH radical scavenger .
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