75 Results for "

gly-phe-

" in MedChemExpress (MCE) Product Catalog:
Products (75)

75 Results for "gly-phe-" in MCE Product Catalog:

4
4 Cited Publications
Art. -Nr.: HY-P0073
CAS. Nr.: 58569-55-4
Synonyms: Met-Enkephalin; Methionine enkephalin; Metenkefalin
Target:  

Opioid Receptor

Forschungsgebiete:  

Neurological Disease Cancer

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-44246
CAS. Nr.: 2413428-36-9
Synonyms: Mc-GGFG-OH
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
loading...
    loading...
Art. -Nr.: HY-148668
CAS. Nr.: 2414254-51-4
Reinheit:  97.37%
Synonyms: SHR-A1811 Drug-linker
Forschungsgebiete:  

Cancer

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM) .
loading...
    loading...
Art. -Nr.: HY-W011063
CAS. Nr.: 21438-66-4
Target:  

Cathepsin

Forschungsgebiete:  

Metabolic Disease

Gly-Phe-β-naphthylamide is a substrate of Cathepsin C (HY-P2922) and belongs to the lysosomal agonist. Gly-Phe-β-naphthylamide can freely pass through the cell membrane and organelle membrane. Gly-Phe-β-naphthylamide will be specifically hydrolyzed by Cathepsin C, ultimately leading to a permeability lysis when it enters the acidic compartment. Gly-Phe-β-naphthylamide can be used to study lysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C .
loading...
    loading...
Art. -Nr.: HY-147164
CAS. Nr.: 2632342-16-4
Reinheit:  99.22%
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate .
loading...
    loading...
Art. -Nr.: HY-131990
CAS. Nr.: 1599440-25-1
Reinheit:  99.22%
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
loading...
    loading...
Art. -Nr.: HY-44235
CAS. Nr.: 1599440-15-9
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
loading...
    loading...
Art. -Nr.: HY-P3669
CAS. Nr.: 200427-88-9
Forschungsgebiete:  

Cancer

Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689) .
loading...
    loading...
Art. -Nr.: HY-131833
CAS. Nr.: 160036-44-2
Reinheit:  99.49%
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
loading...
    loading...
Art. -Nr.: HY-P1449
CAS. Nr.: 187794-49-6
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
loading...
    loading...
Art. -Nr.: HY-45672
CAS. Nr.: 1599440-20-6
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .
loading...
    loading...
Art. -Nr.: HY-P4192
CAS. Nr.: 1817857-75-2
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .
loading...
    loading...
Art. -Nr.: HY-13631M
CAS. Nr.: 1599440-12-6
Reinheit:  95.30%
Forschungsgebiete:  

Cancer

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis.
loading...
    loading...
Art. -Nr.: HY-177442
Synonyms: DS-3939
DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .
loading...
    loading...
Art. -Nr.: HY-136432
CAS. Nr.: 2632342-05-1
Reinheit:  98.81%
Synonyms: Mc-GGFG-PAB-OH
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
loading...
    loading...
Art. -Nr.: HY-45545
CAS. Nr.: 2264011-98-3
Target:  

Drug Intermediate

Forschungsgebiete:  

Others

Fmoc-gly-gly-ph-gly-nh-ch2-o-ch2cooh can be used to synthesize the ADC Linker, LND1067 .
loading...
    loading...
Art. -Nr.: HY-13631F
CAS. Nr.: 3053688-78-8
Reinheit:  99.89%
Forschungsgebiete:  

Cancer

Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research .
loading...
    loading...
Art. -Nr.: HY-W090940
CAS. Nr.: 6234-26-0
Target:  

ADC Linkers

Forschungsgebiete:  

Cancer

H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.
loading...
    loading...
Art. -Nr.: HY-W013998
CAS. Nr.: 3321-03-7
Synonyms: gly-phe; H-gly-phe-OH
Forschungsgebiete:  

Others

Glycyl-L-phenylalanine is a phenylalanine derivative .
loading...
    loading...
Art. -Nr.: HY-153795
CAS. Nr.: 1599439-54-9
Reinheit:  99.09%
Forschungsgebiete:  

Cancer

Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a bioactive drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC). Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is applicable to ADC synthesis and cancer research. Exatecan acts as a DNA Topoisomerase I inhibitor .
loading...
    loading...