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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
immunophilin
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "immunophilin" in MCE Product Catalog:
2
Target:
Research Areas:
GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke .
Research Areas:
GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity .
Cat. No.: HY-106345
CAS No.: 892494-07-4
Target:
Research Areas:
ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and potent neuroprotective activity. ILS-920 binds selectively to the immunophilin FKBP52 and to the β1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 shows 200-fold selectivity for FKBP52 versus FKBP12 .
Cat. No.: HY-125693
CAS No.: 143839-74-1
Target:
Research Areas:
L685818 is a specific immunophilin ligand. L685818 was neuroregenerative and non-neuroprotective in primary brain cultures. L685818 protects dopaminergic neurons from toxic inhibition of MPP+ and 6-OHDA, reduces tyrosine hydroxylase (TH) loss, and promotes neuronal process regeneration. L685818 is also an antifungal reagent for Cryptococcus neoformans .
Cat. No.: HY-121628
CAS No.: 106917-52-6
Flusulfamide is a sulfonanilide Fungicide that effectively inhibits the germination of resting spores of Plasmodiophora brassicae, the pathogen causing clubroot in cruciferous crops. Flusulfamide blocks the developmental process of resting spores from stage 1 to stage 2. By downregulating germination-related genes and upregulating immunophilin genes (such as PbCyp3), it induces abnormal accumulation of the PbCYP3 protein, thereby causing the spores to deplete energy in a state of continuous energy consumption without germination, and reducing their infectivity. Flusulfamide reduces soil ATP content in the early stage of application, but soil microbial biomass gradually recovers 3 days later. Flusulfamide is widely used in research on clubroot control .
Cat. No.: HY-P70405
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FKBP4; HSP Binding immunophilin; FKBP Prolyl Isomerase 4; HSP-Binding immunophilin; FKBP59; Peptidylprolyl Isomerase; FKBP52; FK506 Binding Protein 4; Rotamase; FK506-Binding Protein 4; Peptidyl-Prolyl Cis-Trans Isomerase FKBP4; immunophilin FKBP52; FK506
Cat. No.: HY-P80402
Synonyms: FKBP52, FKBP4, Peptidyl-prolyl cis-trans isomerase FKBP4, PPIase FKBP4, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, 59 kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP51, 52 kDa FKBP, FKBP-52, p59, FKBP-4, HBI
Cat. No.: HY-P87535
Synonyms: FKBP52, FKBP4, Peptidyl-prolyl cis-trans isomerase FKBP4, PPIase FKBP4, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, 59 kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP51, 52 kDa FKBP, FKBP-52, p59, FKBP-4, HBI
Cat. No.: HY-P80401
Synonyms: AIG6, FKBP51, FKBP5, Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin, Rotamase, 51 kDa FKBP, FKBP-51, FKBP-5, p54
Cat. No.: HY-P87541
Synonyms: AIG6, FKBP51, FKBP5, Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin, Rotamase, 51 kDa FKBP, FKBP-51, FKBP-5, p54
Cat. No.: HY-P80400
Synonyms: FKBP1, FKBP12, FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, Calstabin-1, FK506-binding protein 1A, immunophilin FKBP12, Rotamase, 12 kDa FKBP, FKBP-12, FKBP-1A
Cat. No.: HY-P87525
Synonyms: FKBP1, FKBP12, FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, Calstabin-1, FK506-binding protein 1A, immunophilin FKBP12, Rotamase, 12 kDa FKBP, FKBP-12, FKBP-1A
Cat. No.: HY-P70403
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FKBP3; PPIase FKBP3; FKBP Prolyl Isomerase 3; 25 KDa FKBP; FKBP-25; Rotamase; FKBP25; FKBP-3; Peptidyl-Prolyl Cis-Trans Isomerase FKBP3; FK506-Binding Protein 25, T-Cell; Rapamycin-Selective 25 KDa immunophilin; FK506-Binding Protein 3 (25kD); FK506 Bindi
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
