106917-52-6
Chemical Structure
Flusulfamide
- CAS No.: 106917-52-6
- Formula:C13H7Cl2F3N2O4S
- Molecular Weight:415.17
IUPAC Name: 4-chloro-N-(2-chloro-4-nitrophenyl)-3-(trifluoromethyl)benzenesulfonamide
InChIKey: GNVDAZSPJWCIQZ-UHFFFAOYSA-N
SMILES: O=S(NC(C(Cl)=C1)=CC=C1[N+]([O-])=O)(C2=CC=C(C(C(F)(F)F)=C2)Cl)=O
Biological Activity: Flusulfamide is a sulfonanilide Fungicide that effectively inhibits the germination of resting spores of Plasmodiophora brassicae, the pathogen causing clubroot in cruciferous crops. Flusulfamide blocks the developmental process of resting spores from stage 1 to stage 2. By downregulating germination-related genes and upregulating immunophilin genes (such as PbCyp3), it induces abnormal accumulation of the PbCYP3 protein, thereby causing the spores to deplete energy in a state of continuous energy consumption without germination, and reducing their infectivity. Flusulfamide reduces soil ATP content in the early stage of application, but soil microbial biomass gradually recovers 3 days later. Flusulfamide is widely used in research on clubroot control[1][2][3].
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Flusulfamide | Flusulfamide is a sulfonanilide Fungicide that effectively inhibits the germination of resting spores of Plasmodiophora brassicae, the pathogen causing clubroot in cruciferous crops. Flusulfamide blocks the developmental process of resting spores from stage 1 to stage 2. By downregulating germination-related genes and upregulating immunophilin genes (such as PbCyp3), it induces abnormal accumulation of the PbCYP3 protein, thereby causing the spores to deplete energy in a state of continuous energy consumption without germination, and reducing their infectivity. Flusulfamide reduces soil ATP content in the early stage of application, but soil microbial biomass gradually recovers 3 days later. Flusulfamide is widely used in research on clubroot control. | |||||||||||||||||||||
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References
- [1]. Aviantara D B. The effects of fluazinam and flusulfamide on soil ATP microbial biomass[C]//Proceeding of the International Seminar on Chemistry 2008. 2008: 269-272.
- [2]. Ahn, Gyeong-geun, et al. Analytical Method for the Residues of Flusulfamide, a Benzenesulfonamide Fungicide, in Major Agricultural Products [J]. Korean J. Environ. Agric., 2018, 37(1): 57-65.
- [3]. Sasaki T, et al. Effects of flusulfamide on spore germination of Plasmodiophora brassicae[J]. Journal of Pesticide Science, 2024, 49(1): 52-57.
