4 Results for "

naive central memory T cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "naive central memory T cells" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-144987
CAS No.: 2597933-17-8
Purity:  98.84%
Target:  

CD38 LAG-3 Tim3 PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

RBN013209 is an orally active small molecule inhibitor of CD38 with an IC50 of 0.01 to 0.1 μM for human CD38. RBN013209 prevents the conversion of extracellular NAD + to ADPR or cADPR in tumor cells and PBMCs. RBN013209 can be used in the study of tumor. In addition, RBN013209 enables CAR-T cells to maintain the naive state and central memory state, and decreases the expression of cell activation markers and exhaustion-related inhibitory receptors .
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Cat. No.: HY-P990635

Target:  

TGF-β Receptor

Research Areas:  

Cancer

NGM-120 is a fully humanized IgG1 monoclonal antibody targeting GFRAL, which functions by blocking the GDF15-GFRAL axis. NGM-120 reduces serum GDF15 levels, increases body weight, expands central memory and proliferative CD8 + T cell populations, and decreases immunosuppressive and naive regulatory T cell populations. NGM-120 can be used for research on advanced prostate cancer .
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Cat. No.: HY-125881
CAS No.: 1228580-11-7
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist, with EC50 values of 7.12 nM, 517 nM for hS1P1 and hS1P3, respectively. ASP1126 decreases the number of peripheral lymphocytes, naive T cells, central memory T cells and effector memory T cells in the peripheral blood. ASP1126 has the potential to be applied in clinical transplantation with improved safety profile .
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Cat. No.: HY-184003
CAS No.: 3071928-57-6
Target:  

Potassium Channel

Research Areas:  

Inflammation/Immunology

LY3972406 is an orally active, selective Kv1.3 antagonist. LY3972406 acts on chronically stimulated effector memory T cells without affecting naive central memory T cells. LY3972406 induces mild, non-adverse skin irritation in Rattus norvegicus. LY3972406 is applicable for the research of autoimmune diseases .
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