1 Result for "

neuro-protecting

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "neuro-protecting" in MCE Product Catalog:

Cat. No.: HY-147859
CAS No.: 2653349-78-9
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

BChE-IN-8 (compound 20) is an orally active, potent and BBB-penetrated BChE (butyrylcholinesterase) inhibitor, with IC50 values of 0.15 nM (eqBChE, equine serum BChE) and 45.2 nM (hBChE), respectively. High stability of BChE-IN-8 contributes to significantly improved blood concentration and tissue exposure. BChE-IN-8 can exert neuro-protecting and cognition improving properties through multiple modulations, including cholinergic system, Aβ aggregation, neuropeptide levels. BChE-IN-8 can be used for Alzheimer's disease (AD) research .
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