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Results for "

prenyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) AMPK (1) Antibiotic (1) Bacterial (3) Biochemical Assay Reagents (1) Drug Derivative (1) Drug Intermediate (1) Endogenous Metabolite (1) Environmental Pollutants (1) Farnesyl Transferase (2) Fungal (1) GGTase (1) Insecticide (1) Interleukin Related (1) Phosphodiesterase (PDE) (1) PI3K (1) Ras (1) Reactive Oxygen Species (ROS) (2) Sirtuin (1) SOD (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Endocrinology (1) Infection (5) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-N2787

8-Prenylnaringenin 1 Publications Verification	PI3K Akt AMPK Sirtuin Reactive Oxygen Species (ROS) SOD	Cardiovascular Disease Neurological Disease Metabolic Disease Endocrinology Cancer
8-Prenylnaringenin is an orally active prenyl flavonoid. 8-Prenylnaringenin can be isolated from the hop spike Humulus lupulus. 8-Prenylnaringenin activates the PI3K/Akt pathway and the AMPK pathway, upregulates OXPHOS complexes (II, III, and V) and Sirt1, and reduces ROS production and SOD activity. 8-Prenylnaringenin improves muscle atrophy and obesity and inhibits angiogenesis. 8-Prenylnaringenin exhibits anticancer activity against glioblastoma and colon cancer. 8-Prenylnaringenin also has LH/FSH regulatory activity. 8-prenylnaringenin may be used in bone health research .

HY-N2732

6-Prenylapigenin 6-prenyl-4',5,7-trihydroxyflavone; 6-C-prenylapigenin	Others	Cancer
6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells .

HY-W012568

1-Methoxynaphthalene	Reactive Oxygen Species (ROS)	Others
1-Methoxynaphthalene is used as the substrate to investigate the activity of cytochrome c peroxidase (CcP). 1-Methoxynaphthalene also can be used to synthesize prenyl naphthalen-ols .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-N1868

*3-Prenyl-2,4,6-trihydroxybenzophenone*	Others	Others
3-Prenyl-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa .

HY-U00327

Prenyl-IN-1	Farnesyl Transferase GGTase	Neurological Disease
Prenyl-IN-1 is a protein prenylation inhibitor, especially a geranylgeranyltransferase (GGT) or a farnesyltransferase (FT) inhibitor, exhibiting potent activity against oxidative stress, and particularly in the treatment of Parkinson's Disease.

HY-N1833

*3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone*	Others	Cancer
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone displays cytotoxicity of 1.32, 3.92 and 5.22 μm against the human cervical carcinoma HeLa, human breast carcinoma MCF-7, and human hepatocarcinoma Hep3B cells .

HY-10062

AZD3409 EBP-921	Akt Farnesyl Transferase	Cancer
AZD3409 is a prenyl inhibitor that exhibits inhibitory activity against both farnesyl transferase and geranylgeranyl transferase I. AZD3409 inhibits the growth of breast cancer cells, with IC₅₀s of 220 nM (MDA-MB-468), 180 nM (MDA-MB-361), and 290 nM (SK-Br-3). AZD3409 significantly reduces the activation level of AKT in breast cancer cell lines. AZD3409 induces G0/G1 phase arrest in MDA-MB-468 cells, causes G2/M phase arrest in MDA-MB-361 cells. AZD3409 can be used for the study of breast cancer .

HY-N8101

*Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate*	Others	Others
Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate is a natural product .

HY-N13828

*1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole*	Bacterial Interleukin Related	Infection Inflammation/Immunology
1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC₅₀ values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases .

HY-N10007

Dodoviscin J	Others	Others
Dodoviscin J is a prenyl flavonol derivative can be isolated from the aerial parts of Dodonaea viscosa .

HY-P10210

Paenilagicin	Antibiotic Bacterial	Infection
Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria .

HY-164513

NHTD	Ras Phosphodiesterase (PDE)	Cancer
NHTD is a KRAS-PDEδ inhibitor. NHTD targets the prenyl-binding pocket of PDEδ, altering the cellular localization of KRAS, thereby inhibiting the proliferation of KRAS-mutant cancer cells and inducing apoptosis. NHTD can be used for research on KRAS-driven non-small cell lung cancer (NSCLC) .

HY-W010415

Prenyl acetate	Environmental Pollutants Insecticide	Infection
Prenyl acetate is an insecticide. At low concentrations, prenyl acetate exhibits an attractant effect on worker ants of the red imported fire ant, and it elicits strong antennal electroantennogram (EAG) responses in all castes of the red imported fire ant. Prenyl acetate shows low toxicity to mammals. It can be used in research related to the control of the red imported fire ant (Solenopsis invicta) .

HY-N1627

*2-Prenyl-1-naphthol*	Others	Others
2-Prenyl-1-naphthol is a Sesquiterpenoids product that can be isolated from the herbs of Catalpa ovata .

HY-N13823

6'-Prenylisorhamnetin 5,7,4'-Trihydroxy-6'-prenyl-3'-methoxyflavonol	Drug Derivative	Others
6'-Prenylisorhamnetin (5,7,4'-Trihydroxy-6'-prenyl-3'-methoxyflavonol) is a natural flavonoid.

HY-W404362

2,4,6-Trihydroxy-3-prenylacetophenone	Drug Intermediate	Others
2,4,6-Trihydroxy-3-prenylacetophenone (compound 13) is a prenylated acetophenone derivative that can be used as a synthetic intermediate .

HY-N17390

Citaldoxime	Endogenous Metabolite Fungal	Infection
Citaldoxime (Compound 7) is a γ-radiation-induced antifungal stress metabolite that can be found in Citrus plants .

HY-E71156

1,4-Dihydroxy-2-naphthoate polyprenyltransferase	Biochemical Assay Reagents	Others
1,4-Dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) catalyses a step in the synthesis of menaquinone, in which the prenyl chain synthesized by polyprenyl diphosphate synthase is transferred to 1,4-Dihydroxy-2-naphthoate (DHNA) . 1,4-Dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) is an inner membrane protein, with the C-terminus located in the periplasm. 1,4-Dihydroxy-2-naphthoate polyprenyltransferase (EC 2.5.1.74) is highly specific for DHNA but not for a specific length of the prenyl chain.

Cat. No.	Nombre del producto	Target	Research Area

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-P10210

Paenilagicin	Antibiotic Bacterial	Infection
Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria .

8-Prenylnaringenin 1 Publications Verification	Structural Classification Flavonoids Classification of Application Fields Humulus lupulus L. Flavonones Phenols Polyphenols Plants Moraceae Disease Research Fields Source Classification Cancer	PI3K Akt AMPK Sirtuin Reactive Oxygen Species (ROS) SOD
8-Prenylnaringenin is an orally active prenyl flavonoid. 8-Prenylnaringenin can be isolated from the hop spike Humulus lupulus. 8-Prenylnaringenin activates the PI3K/Akt pathway and the AMPK pathway, upregulates OXPHOS complexes (II, III, and V) and Sirt1, and reduces ROS production and SOD activity. 8-Prenylnaringenin improves muscle atrophy and obesity and inhibits angiogenesis. 8-Prenylnaringenin exhibits anticancer activity against glioblastoma and colon cancer. 8-Prenylnaringenin also has LH/FSH regulatory activity. 8-prenylnaringenin may be used in bone health research .

6-Prenylapigenin 6-prenyl-4',5,7-trihydroxyflavone; 6-C-prenylapigenin	Structural Classification Flavonoids Flavones Maclura pomifera (Raf.) Schneid. Plants Moraceae Source Classification	Others
6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells .

*3-Prenyl-2,4,6-trihydroxybenzophenone*	Xanthones Guttiferae Phenols Plants Garcinia cowa Roxb. Source Classification	Others
3-Prenyl-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa .

*3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone*	Flavonoids Classification of Application Fields Flavones Phenols Polyphenols Plants Moraceae Disease Research Fields Morus alba Linn. Source Classification Cancer	Others
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone displays cytotoxicity of 1.32, 3.92 and 5.22 μm against the human cervical carcinoma HeLa, human breast carcinoma MCF-7, and human hepatocarcinoma Hep3B cells .

*Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate*	Productos naturales Classification of Application Fields Other Diseases Rubiaceae Plants Disease Research Fields Source Classification Rubia cordifolia L.	Others
Methyl 1,4-bisglucosyloxy-3-prenyl-2-naphthoate is a natural product .

*1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole*	Alkaloids Rutaceae Murraya koenigii (L.) Spreng Carbazole Alkaloids Plants Indole Alkaloids Source Classification	Bacterial Interleukin Related
1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC₅₀ values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases .

Dodoviscin J	Flavonoids Flavones Dodonaea viscosa (L.) Jacq. Sapindaceae Plants Source Classification	Others
Dodoviscin J is a prenyl flavonol derivative can be isolated from the aerial parts of Dodonaea viscosa .

Prenyl acetate	Structural Classification Productos naturales Rosaceae Plants Source Classification	Environmental Pollutants Insecticide
Prenyl acetate is an insecticide. At low concentrations, prenyl acetate exhibits an attractant effect on worker ants of the red imported fire ant, and it elicits strong antennal electroantennogram (EAG) responses in all castes of the red imported fire ant. Prenyl acetate shows low toxicity to mammals. It can be used in research related to the control of the red imported fire ant (Solenopsis invicta) .

*2-Prenyl-1-naphthol*	Catalpa ovata G. Don Phenols Bignoniaceae Plants Source Classification	Others
2-Prenyl-1-naphthol is a Sesquiterpenoids product that can be isolated from the herbs of Catalpa ovata .

6'-Prenylisorhamnetin 5,7,4'-Trihydroxy-6'-prenyl-3'-methoxyflavonol	Structural Classification Flavonols Platanus acerifolia Aiton) Willd. Flavonoids Platanaceae Plants Source Classification	Drug Derivative
6'-Prenylisorhamnetin (5,7,4'-Trihydroxy-6'-prenyl-3'-methoxyflavonol) is a natural flavonoid.

2,4,6-Trihydroxy-3-prenylacetophenone	Structural Classification Carlina acaulis L. Phenols Polyphenols Umbelliferae Plants Source Classification	Drug Intermediate
2,4,6-Trihydroxy-3-prenylacetophenone (compound 13) is a prenylated acetophenone derivative that can be used as a synthetic intermediate .

Citaldoxime	Structural Classification Productos naturales Rutaceae Plants Citrus reticulata Blanco Source Classification	Endogenous Metabolite Fungal
Citaldoxime (Compound 7) is a γ-radiation-induced antifungal stress metabolite that can be found in Citrus plants .

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prenyl

Inhibitors & Agonists

Peptides

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Natural
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