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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
pro-caspase-3 cleavage
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "pro-caspase-3 cleavage" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-P701341
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CASP3; protein Yama; caspase 3; caspase-3; Apopain; CASP-3; CPP32; CPP-32; CPP32B; SCA-1; caspase 3, Apoptosis-Related Cysteine Peptidase; Yama; caspase 3, Apoptosis-Related Cysteine protease; PARP cleavage protease; SREBP cleavage Activity 1; procaspase3
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P72874
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CASP3; protein Yama; caspase 3; caspase-3; Apopain; CASP-3; CPP32; CPP-32; CPP32B; SCA-1; caspase 3, Apoptosis-Related Cysteine Peptidase; Yama; caspase 3, Apoptosis-Related Cysteine protease; PARP cleavage protease; SREBP cleavage Activity 1; procaspase3
Species:
Human
Source:
E. coli
Cat. No.: HY-142690
CAS No.: 2763368-89-2
HDAC-IN-27 (Compound 11h) is a potent, orally active class I HDAC-selective inhibitor with IC50 values ranging from 0.43 to 3.01 nM against HDAC1-3. HDAC-IN-27 exhibits both in vivo and in vitro antitumor activity. HDAC-IN-27 demonstrates significant anti-proliferative activity against acute myeloid leukemia (AML) cell lines by inducing apoptosis and histone acetylation (AcHH3 and AcHH4). HDAC-IN-27 can be used for research in acute myeloid leukemia (AML) .
Cat. No.: HY-142690A
CAS No.: 3069831-25-7
HDAC-IN-27 dihydrochloride (Compound 11h) is a potent, orally active class I HDAC-selective inhibitor with IC50 values ranging from 0.43 to 3.01 nM against HDAC1-3. HDAC-IN-27 dihydrochloride exhibits both in vivo and in vitro antitumor activity. HDAC-IN-27 dihydrochloride demonstrates significant anti-proliferative activity against acute myeloid leukemia (AML) cell lines by inducing apoptosis and histone acetylation (AcHH3 and AcHH4). HDAC-IN-27 dihydrochloride can be used for research in acute myeloid leukemia (AML) .
Research Areas:
2-Chlorohexadecanoic acid, an inflammatory lipid mediator, interferes with protein palmitoylation,induces ER-stress markers, reduced the ER ATP content, and activates transcription and secretion of IL-6 as well as IL-8.2-Chlorohexadecanoic acid disrupts the mitochondrial membrane potential and induces procaspase-3 and PARP cleavage.2-Chlorohexadecanoic acid can across blood-brain barrier (BBB) and compromises ER- and mitochondrial functions in the human brain endothelial cell line hCMEC/D3 .
Cat. No.: HY-P79267
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CASP3; protein Yama; caspase 3; caspase-3; Apopain; CASP-3; CPP32; CPP-32; CPP32B; SCA-1; caspase 3, Apoptosis-Related Cysteine Peptidase; Yama; caspase 3, Apoptosis-Related Cysteine protease; PARP cleavage protease; SREBP cleavage Activity 1; procaspase3
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
