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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
prominent
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "prominent" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: D-Glucosamine; Chitosamine
12
12 Publications Verification
Synonyms: D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride
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5
Linifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis .
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1 Cited Publications
Cat. No.: HY-N9457
CAS No.: 60696-62-0
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1 Cited Publications
Cat. No.: HY-P1502
CAS No.: 61214-51-5
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1
1 Cited Publications
Cat. No.: HY-147803
Purity: 98.07%
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TrxR-IN-5 (compound 4f) is a potent TrxR (thioredoxin reductase) inhibitor, with an IC50 of 0.16 μM. TrxR-IN-5 increases the levels of ROS, thus leading to potent antiproliferative effects. TrxR-IN-5 exhibits prominent anticacer and anti-metastasis effects .
Cat. No.: HY-16212
CAS No.: 146478-72-0
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Cat. No.: HY-N16308
CAS No.: 3091879-77-2
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Cat. No.: HY-W014180
CAS No.: 39145-52-3
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Animals Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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JNJ-8003 is a potent and orally active non-nucleoside RSV polymerase inhibitor with an IC50 of 0.29 nM. JNJ-8003 targets the L protein polymerase complex of RSV (IC50 = 0.67 nM), and blocks the transcription and replication of the viral genome by inhibiting the activity of RNA-dependent RNA polymerase (RdRp). JNJ-8003 displays subnanomolar activity in vitro as well as prominent efficacy in mice and a neonatal lamb models. JNJ-8003 can be used for the study of respiratory syncytial virus (RSV) .
Cat. No.: HY-N0733S3
Synonyms: D-(+)-Glucosamine-6-13C hydrochloride; Chitosamine-6-13C hydrochloride
Synonyms: MPH
Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC50s of 3.2 nM and 1.9 nM, respectively. Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo .
Cat. No.: HY-N1247
CAS No.: 185213-52-9
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Terpenoids Sesquiterpenes Amorpha fruticosaL. Plants Compositae Disease Research Fields Cancer
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Synonyms: D-(+)-Glucosamine hydrochloride (Standard); Chitosamine hydrochloride (Standard)
Cat. No.: HY-W013482
CAS No.: 94-18-8
Synonyms: Benzyl Paraben
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Benzyl 4-hydroxybenzoate is a prominent material. Benzyl 4-hydroxybenzoate can be used as an excipient, such as bacteriostatic agent, preservative. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
Cat. No.: HY-N0733S
CAS No.: 84247-63-2
Synonyms: D-(+)-Glucosamine-13C hydrochloride; Chitosamine-13C hydrochloride
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Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H2S) .
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Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, is discovered. N-Palmitoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Its function is currently under investigation.
Cat. No.: HY-157343B
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GD3 Ganglioside ammonium is an Apoptosis inducer and biomarker for mouse neural stem cells. GD3 Ganglioside ammonium expresses in neural stem cells and the subventricular zone of the adult mouse brain. GD3 Ganglioside ammonium targets the mitochondrial permeability transition pore complex, induces pore opening, dissipates mitochondrial transmembrane potential, triggers Mitochondrial swelling, releases pro-apoptotic factors, and activates Caspase-9. GD3 Ganglioside ammonium is applicable to research related to glioblastoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
