1. NF-κB
    Immunology/Inflammation
    Metabolic Enzyme/Protease
    Autophagy
  2. Endogenous Metabolite
    Reactive Oxygen Species
    HIF/HIF Prolyl-Hydroxylase
    Autophagy
  3. Glucosamine sulfate

Glucosamine sulfate (Synonyms: D-Glucosamine sulfate)

Cat. No.: HY-N0487
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Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.

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Glucosamine sulfate Chemical Structure

Glucosamine sulfate Chemical Structure

CAS No. : 29031-19-4

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Description

Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Glucosamine sulfate (D-Glucosamine sulfate) exhibits dose-dependent DPPH antioxidant activity[2].
Glucosamine sulfate treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins[3].
Glucosamine sulfate significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells[4].

Formula

C₆H₁₃NO₅.xH₂O₄S

CAS No.

29031-19-4

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Glucosamine sulfate
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HY-N0487
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