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pyrrole group

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By Targets:	Biochemical Assay Reagents (4) Drug Metabolite (1) Environmental Pollutants (1) Oxidative Phosphorylation (2) Parasite (2) Reference Standards (2)
By Research Areas:	Metabolic Disease (2)
Click Chemistry:	Azide (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0840

Chlorfenapyr	Environmental Pollutants Parasite Oxidative Phosphorylation	Metabolic Disease
Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .

HY-77817

Pyrrole-2-carboxaldehyde 2-Formylpyrrole	Others	Others
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase. Pyrrole-2-carboxaldehyde is a five membered N-heterocyclic system containing pyrrole group as a proton donor and carbonyl group as a proton acceptor .

HY-32959

N-Boc-2-pyrroleboronic acid	Biochemical Assay Reagents	Others
N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester .

HY-W007392

Methyl 4-bromo-1H-pyrrole-2-carboxylate Methyl 4-bromopyrrole-2-carboxylate	Biochemical Assay Reagents	Others
Methyl 4-bromo-1H-pyrrole-2-carboxylate (Methyl 4-bromopyrrole-2-carboxylate) is a biologically active pyrrole derivative. Methyl 4-bromo-1H-pyrrole-2-carboxylate can be used in studies on the development of pyrrole-related biosensors .

HY-B0840R

Chlorfenapyr (Standard)	Oxidative Phosphorylation Parasite Reference Standards	Metabolic Disease
Chlorfenapyr (Standard) is the analytical standard of Chlorfenapyr. This product is intended for research and analytical applications. Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .

HY-77817R

Pyrrole-2-carboxaldehyde (Standard) 2-Formylpyrrole (Standard)	Reference Standards Others	Others
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) (Standard) is the analytical standard of Pyrrole-2-carboxaldehyde. This product is intended for research and analytical applications. Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase. Pyrrole-2-carboxaldehyde is a five membered N-heterocyclic system containing pyrrole group as a proton donor and carbonyl group as a proton acceptor .

HY-W394551

Methyl 3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate	Biochemical Assay Reagents	Others
Methyl 3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate is a small pyrrolidone molecule which features two bromine atoms and a methyl ester. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time. The methyl ester can be saponified to link this molecule to amines to form larger structures.

HY-183022

3-Azidopropyl-1-maleimide	Biochemical Assay Reagents	Others
1-(3-Azidopropyl)-1H-pyrrole-2,5-dione is a maleimide derivative with a 3-azidopropyl substituent, used to introduce an azide functional group to bovine serum albumin (BSA). 1-(3-Azidopropyl)-1H-pyrrole-2,5-dione reacts with the free, solvent-accessible thiol group of BSA to produce azide-functionalized BSA, which is used in click chemistry to form a TLL-BSA hetero-dimer .

HY-W714239

Spirotetramat-keto-hydroxy	Drug Metabolite	Others
Spirotetramat-keto-hydroxy is a metabolite of Spirotetramat (HY-120253). Spirotetramat is an insecticide .

Cat. No.	Product Name

HY-L167

Boronic Acid Compound Library	163 compounds
Boric acid is a stable and usually non-toxic group widely used in modern synthesis to form C-C and C-heteroatom bonds. Boric acid exhibits exquisite reversible coordination characteristics and can be explored as a molecular construction tool, with specific mechanisms for controlling the structure and biological characteristics of bioconjugates. Boric acid has various activities, such as anticancer, antibacterial, and antiviral activities. In drugs, boric acid mainly exists in the form of arylboronic acid. In addition to this form, heterocycles containing boric acid, such as pyridine, pyrrole, and indole derivatives, are also very useful in pharmaceutical chemistry. Molecular modification by introducing boric acid groups into bioactive molecules has been shown to alter selectivity, physicochemical, and pharmacokinetic characteristics, and improve existing activity. MCE designs a unique collection of 163 boronic acid compounds. It is a good tool to be used for research on cancer and other diseases.

Boronic Acid Compound Library

163 compounds

Boric acid is a stable and usually non-toxic group widely used in modern synthesis to form C-C and C-heteroatom bonds. Boric acid exhibits exquisite reversible coordination characteristics and can be explored as a molecular construction tool, with specific mechanisms for controlling the structure and biological characteristics of bioconjugates. Boric acid has various activities, such as anticancer, antibacterial, and antiviral activities. In drugs, boric acid mainly exists in the form of arylboronic acid. In addition to this form, heterocycles containing boric acid, such as pyridine, pyrrole, and indole derivatives, are also very useful in pharmaceutical chemistry. Molecular modification by introducing boric acid groups into bioactive molecules has been shown to alter selectivity, physicochemical, and pharmacokinetic characteristics, and improve existing activity.

MCE designs a unique collection of 163 boronic acid compounds. It is a good tool to be used for research on cancer and other diseases.

Cat. No.	Product Name	Type

HY-32959

N-Boc-2-pyrroleboronic acid	Biochemical Assay Reagents
N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester .

N-Boc-2-pyrroleboronic acid

Biochemical Assay Reagents

N-Boc-2-pyrroleboronic acid is an organic synthesis intermediate used primarily in the synthesis of chiral pharmaceutical molecules and biologically active molecules. The boronic acid on the pyrrole ring can participate in Suzuki coupling reactions. The boronic acid can be oxidized to a hydroxyl group under the action of nitrogen oxides, and after tautomerization, it can be further transformed into 2-oxo-2,5-dihydro-1-pyrrolecarboxylic acid tert-butyl ester .

HY-W007392

Methyl 4-bromo-1H-pyrrole-2-carboxylate Methyl 4-bromopyrrole-2-carboxylate	Biochemical Assay Reagents
Methyl 4-bromo-1H-pyrrole-2-carboxylate (Methyl 4-bromopyrrole-2-carboxylate) is a biologically active pyrrole derivative. Methyl 4-bromo-1H-pyrrole-2-carboxylate can be used in studies on the development of pyrrole-related biosensors .

Pyrrole-2-carboxaldehyde 2-Formylpyrrole	Alkaloids Structural Classification other families Pyrrole Alkaloids Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Others
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase. Pyrrole-2-carboxaldehyde is a five membered N-heterocyclic system containing pyrrole group as a proton donor and carbonyl group as a proton acceptor .

Pyrrole-2-carboxaldehyde (Standard) 2-Formylpyrrole (Standard)	Alkaloids Structural Classification other families Pyrrole Alkaloids Plants Source Classification	Reference Standards Others
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) (Standard) is the analytical standard of Pyrrole-2-carboxaldehyde. This product is intended for research and analytical applications. Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase. Pyrrole-2-carboxaldehyde is a five membered N-heterocyclic system containing pyrrole group as a proton donor and carbonyl group as a proton acceptor .

Cat. No.	Product Name		Classification

HY-183022

3-Azidopropyl-1-maleimide		Azide
1-(3-Azidopropyl)-1H-pyrrole-2,5-dione is a maleimide derivative with a 3-azidopropyl substituent, used to introduce an azide functional group to bovine serum albumin (BSA). 1-(3-Azidopropyl)-1H-pyrrole-2,5-dione reacts with the free, solvent-accessible thiol group of BSA to produce azide-functionalized BSA, which is used in click chemistry to form a TLL-BSA hetero-dimer .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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pyrrole group

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