28 Results for "

quassinoids

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "quassinoids" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0841
CAS No.: 25514-31-2
Synonyms: Dihydrobrusatol; NSC310616
Bruceine A (Dihydrobrusatol) is a natural quassinoid. Bruceine A is an inhibitor of parasites, NF-κB, and PFKFB4 (Kd: 44 nM). Bruceine A is an activator of P38α MAPK. Bruceine A has antiparasitic activity. Bruceine A has antitumor activity and inhibits cancer cell migration. Bruceine A blocks the cell cycle and induces apoptosis. Bruceine A can be used in parasites, pancreatic cancer, and breast cancer research .
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2
2 Cited Publications
Cat. No.: HY-N0840
CAS No.: 41451-75-6
Synonyms: (-)-Bruceantin; NCI165563; NSC165563
Bruceantin ((-)-Bruceantin) is a quassinoid found in B. javanica. Bruceantin activates caspase signaling pathway, causes the mitochondrial dysfunction, inhibits cell proliferation, induces cell differentiation and apoptosis. Bruceantin exhibits anti-leukemia and antiprotozoal activities .
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Cat. No.: HY-N4327
CAS No.: 23062-24-0
Eurycomalactone is an active quassinoid could be isolated from Eurycoma longifolia Jack. Eurycomalactone is a potent NF-κB inhibitor with an IC50 value of 0.5 μM. Eurycomalactone inhibits protein synthesis and depletes cyclin D1. Eurycomalactone enhances radiosensitivity through arrest cell cycle at G2/M phase and delayed DNA double-strand break repair. Eurycomalactone inhibits the activation of AKT/NF-κB signaling, induces apoptosis and enhances chemosensitivity to Cisplatin (HY-17394) .
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Cat. No.: HY-N8146
CAS No.: 53729-52-5
Bruceantinol is a quassinoid that can be isolated from Brucea javanica, inhibits pepper mottle virus (PepMoV) in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol has potent anti-leukemic activity. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50 = 2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc. Bruceantinol binds with CDK2/4/6 to facilitate protein degradation through proteasome pathway. Bruceantinol can dose- and time-dependently reduces the cell growth, impede cell proliferation, disrupts the cell cycle, and induces necrosis in MCF-7 cells and apoptosis in MDA-MB-231 cells .
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Cat. No.: HY-N3015
CAS No.: 21586-90-3
Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect . Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose .
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Cat. No.: HY-N8995
CAS No.: 63306-30-9
Bruceoside A, an abundant quassinoid glycoside in Fructus Bruceae, possesses anti-cancer activity .
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Cat. No.: HY-N10313
CAS No.: 53730-90-8
Dehydrobruceine B, a quassinoid, can be isolated from Brucea javanica. Dehydrobruceine B shows a synergistic effect with Cisplatin (HY-17394) to induce apoptosis via mitochondrial method. Dehydrobruceine B increases apoptosis-inducing factor (AIF) and Bax expression and suppresses Keap1-Nrf2 .
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Cat. No.: HY-N4257
CAS No.: 95258-15-4
Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity .
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Cat. No.: HY-N7338
CAS No.: 95258-12-1
Yadanziolide C is a quassinoid with antiproliferative and differentiation-inducing properties in promyelocytic HL-60 cells .
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Cat. No.: HY-N7532
CAS No.: 99132-95-3
Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM .
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Cat. No.: HY-133096
CAS No.: 101559-98-2
Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima .
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Cat. No.: HY-N12151
CAS No.: 22611-34-3
Chaparrinone is a quassinoid that can be isolated from the root of Eurycoma harmandiana. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC50: 0.037 and 0.34 μg/mL respectively) .
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Cat. No.: HY-N7194
CAS No.: 99132-97-5
Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM) .
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Cat. No.: HY-125067
CAS No.: 79439-84-2
Yadanzioside P is an antileukemic quassinoid glycoside. Yadanzioside P can be isolated from the seeds of Brucea javanica (L.). Yadanzioside P can be used for the research of cancer .
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Cat. No.: HY-N10368
CAS No.: 103630-27-9
Shinjulactone M is a quassinoid isolated from various parts of Ailanthus species. Ailanthus, an important genus of the Simaroubaceae family, can be used as an febrifuge (antimalarial) and anthelmintic, and is given for the research of chronic bronchitis, epilepsy and asthma .
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Cat. No.: HY-N9325
CAS No.: 138874-44-9
Synonyms: 13β,21-Dihydroxyeurycomanone
Pasakbumin D is a quassinoid and can be used for the research of cancer .
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Cat. No.: HY-N7189
CAS No.: 95258-16-5
Yadanzioside C is a quassinoid glucoside found in seeds of Brucea amarissima .
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Cat. No.: HY-123083
CAS No.: 126149-71-1
Javanicin C is a quassinoid that can be isolated from the bark of Picrasma javanica .
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Cat. No.: HY-126613
CAS No.: 85643-76-1
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Others

Laurycolactone A is a quassinoid with a C18 basic skeleton. Laurycolactone A can be isolated from Eurycoma longifolia .
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Cat. No.: HY-N8399
CAS No.: 95258-13-2
Yadanziolide B, a natural quassinoid, is a potential H5N1 neuraminidase inhibitor .
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