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retinol derivative

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By Targets:	Drug Derivative (1) Apoptosis (1) Cytochrome P450 (1) Drug Metabolite (2) Endogenous Metabolite (1) Isotope-Labeled Compounds (1) RAR/RXR (2) Reference Standards (1) UGT (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (1)

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Isotope-Labeled Compounds

Targets Recommended: Drug Derivative

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7495

all-trans-Anhydro Retinol Anhydrovitamin A	Drug Metabolite	Metabolic Disease
all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .

HY-125904

4-Hydroxyretinoic acid 1 Publications Verification	RAR/RXR UGT Cytochrome P450 Apoptosis Drug Derivative	Neurological Disease Inflammation/Immunology Cancer
4-Hydroxyretinoic acid (4-HRA) is a derivative of Retinoic acid (HY-14649). 4-Hydroxyretinoic acid is formed via the catalysis of retinol by cytochrome P-450 isoenzymes. 4-Hydroxyretinoic acid also serves as a substrate for UDP-glucuronosyltransferase (s) and recombinant UGT2B7. 4-Hydroxyretinoic acid binds to the nuclear receptor RAR (Retinoic Acid Receptor), activates RAR and RXR-alpha, subsequently regulates gene expression and cell differentiation, and induces cancer cell apoptosis (Apoptosis). 4-Hydroxyretinoic acid also participates in multiple physiological processes such as immunoregulation, neuroprotection and antioxidation .

HY-16760

9-cis-Retinol acetate 9-cis-Vitamin A acetate; Zuretinol acetate	Others	Others
9-cis-Retinol acetate is a retinal derivative.

HY-W442049

Hydroxypinacolone retinoate HPR	RAR/RXR	Inflammation/Immunology
Hydroxypinacolone retinoate (HPR) is a retinol derivative, which binds directly with retinoic acid receptors (RARs). Hydroxypinacolone retinoate, when used in combination with Retinyl propionate, can be used in anti-skin aging research .

HY-16760S

9-cis-Retinol acetate-d5 9-cis-Vitamin A acetate-d₅; Zuretinol acetate-d₅	Isotope-Labeled Compounds	Others
9-cis-Retinol acetate-d₅ is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative .

HY-N7495R

all-trans-Anhydro Retinol (Standard) Anhydrovitamin A (Standard)	Reference Standards Drug Metabolite	Metabolic Disease
all-trans-Anhydro Retinol (Standard) (Anhydrovitamin A (Standard)) is the analytical standard of all-trans-Anhydro Retinol (HY-N7495). This product is intended for research and analytical applications. all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .

HY-115731

Tocol Desmethyltocopherol; DL-Tocol; rac-Tocol	Endogenous Metabolite	Metabolic Disease
(±)-Tocol is a synthetic vitamin E derivative.nlike (±)-α-tocopherol, (±)-tocol does not suppress retinol-induced erythrocyte hemolysis or increase microviscosity of rat liver phosphatidylcholine (PC) liposomes.

HY-W587809

All-trans-Retinyl oleate Retinyl oleate	Others	Others
All-trans-Retinyl oleate (Retinyl oleate) is a synthetic ester formed from the combination of Retinol (vitamin A) and oleic acid. All-trans-Retinyl oleate belongs to the class of retinoids, which are derivatives of vitamin A.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7495

all-trans-Anhydro Retinol Anhydrovitamin A	Classification of Application Fields Terpenoids Metabolic Disease Diterpenoids Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .

HY-N7495R

all-trans-Anhydro Retinol (Standard) Anhydrovitamin A (Standard)	Structural Classification Terpenoids Diterpenoids Endogenous metabolite Source Classification	Reference Standards Drug Metabolite
all-trans-Anhydro Retinol (Standard) (Anhydrovitamin A (Standard)) is the analytical standard of all-trans-Anhydro Retinol (HY-N7495). This product is intended for research and analytical applications. all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .

Cat. No.	Product Name	Chemical Structure

HY-16760S

9-cis-Retinol acetate-d5
9-cis-Retinol acetate-d₅ is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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retinol derivative

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Isotope-Labeled Compounds

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