21 Results for "

type IV collagen

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "type IV collagen" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-E70005D
CAS No.: 9001-12-1
Synonyms: collagenase, type IV
Target:  

MMP

Research Areas:  

Others

Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin.

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6
6 Cited Publications
Cat. No.: HY-P81227
Synonyms: collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; collagen I alpha 1 polypeptide; collagen I alpha 2 polypeptide; collagen Of Skin Tendon And Bone; collagen type 1; collagen type I alpha 1; collagen type I alpha 2; OI4; Osteogenesis Imperfecta type IV; Pro alpha 1(I) collagen; type I procollagen; CO1A1_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat, Rabbit

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4
4 Cited Publications
Cat. No.: HY-P1408
CAS No.: 404882-00-4
Target:  

Integrin VEGFR

Research Areas:  

Cancer

Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .
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4
4 Cited Publications
Cat. No.: HY-P1408A
Target:  

Integrin

Research Areas:  

Cancer

Obtustatin triacetate is a 41-residue non-RGD disintegrin. Obtustatin triacetate can be isolated from the venom of Vipera lebetina obtusa. Obtustatin triacetate is a potent and selective inhibitor of integrin α1β1 adhesion to type IV collagen. Obtustatin triacetate inhibits angiogenesis and may be used in cancer research .
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1
1 Cited Publications
Cat. No.: HY-P2975
CAS No.: 114956-81-9
Synonyms: Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)
Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.
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1
1 Cited Publications
Cat. No.: HY-P81101
Synonyms: COL 3A1; COL3A1; collagen alpha 1(III) chain; collagen III alpha 1 chain precursor; collagen III alpha 1 polypeptide; collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant); collagen type III alpha 1; collagen type III alpha; EDS4A; Ehlers Danlos syndrome type IV, autosomal dominant; Fetal collagen; type III collagen; CO3A1_HUMAN; collagen alpha-1(III) chain; type III collagen; type III preprocollagen alpha 1 chain.

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Dog, Rabbit

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Cat. No.: HY-131577A
CAS No.: 42613-33-2
Synonyms: Dispase I
Target:  

Collagen

Research Areas:  

Others

Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
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Cat. No.: HY-P10709
CAS No.: 847058-45-1
Target:  

Collagen

Research Areas:  

Cardiovascular Disease Cancer

CREKA peptide is a selective non-covalent binding agent targeting fibrin, type IV collagen, and fibronectin, often used as a targeting ligand to modify delivery carriers. CREKA peptide specifically recognizes fibrin, fibronectin, and type IV collagen that are excessively deposited in the tumor microenvironment or fibrotic tissue, mediating the targeted accumulation of the carrier at the lesion site and promoting drug internalization into target cells (such as cancer cells and activated hepatic stellate cells). CREKA peptide can enhance targeted delivery efficiency, increase drug concentration at the lesion site, and reduce systemic side effects .
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Cat. No.: HY-W442049
CAS No.: 893412-73-2
Synonyms: HPR
Target:  

RAR/RXR

Research Areas:  

Inflammation/Immunology

Hydroxypinacolone retinoate (HPR) is a direct-binding agonist of retinoic acid receptor (RAR). Hydroxypinacolone retinoate has low irritation and high stability; when formulated into nanoparticles, its transdermal efficiency is enhanced, allowing it to penetrate deep into the dermis and achieve sustained release. When used in combination with Retinyl propionate, hydroxypinacolone retinoate promotes fibroblast proliferation and upregulates the gene expression of type IV collagen, CRBP-I and RARB. Hydroxypinacolone retinoate can be used in research related to skin wrinkles and skin aging .
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Cat. No.: HY-P11794
CAS No.: 119975-51-8
Target:  

Collagen

Research Areas:  

Others

Type IV collagen peptide is a cell-binding ligand peptide derived from type IV collagen. (The sequence is TAGSCLRKFSTM) .
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Cat. No.: HY-171657
CAS No.: 411233-11-9
4'-Acetoxy resveratrol is a Resveratrol (HY-16561) derivative. 4'-Acetoxy resveratrol upregulates gene expression of elastin, collagen types III and IV, superoxide dismutase (SOD), and catalase (CAT), while downregulating interleukins (IL-1A, IL-1R2, IL-6, IL-8) and cyclooxygenase-2 (COX-2) in human skin models. 4'-Acetoxy resveratrol can be used for skin reasearch .
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Cat. No.: HY-P11794A
Target:  

Collagen

Research Areas:  

Others

Type IV collagen peptide acetate is a cell-binding ligand peptide derived from type IV collagen. (The sequence is TAGSCLRKFSTM) .
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Cat. No.: HY-P86639
Synonyms: Arresten; BSVD; CO4A1_HUMAN; COL4A1; COL4A1 NC1 domain; COL4A2; COL4A3; COL4A4; COL4A5; collagen alpha-1; IV; chain; collagen IV Alpha 1 Polypeptide; collagen IV Alpha 2 Polypeptide; collagen Of Basement Membrane Alpha 1 Chain; collagen Of Basement Membrane Alpha 2 Chain; collagen type IV Alpha 1; collagen type IV alpha 1 chain; collagen type IV Alpha 2; collagen type IV Alpha 3; collagen type IV Alpha 4; collagen type IV Alpha 5; RatOR

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human

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Cat. No.: HY-P81201
Synonyms: Arresten; Canstatin; COL4A1; HANAC; ICH; POREN1; collagen Alpha 1(IV) Chain; collagen IV Alpha 1 Polypeptide; collagen Of Basement Membrane Alpha 1 Chain; collagen Of Basement Membrane Alpha 2 Chain; collagen type IV Alpha 1; DKFZp686I14213; FLJ22259; collagen alpha-1(IV) chain preproprotein; collagen alpha-1(IV) chain preproprotein; Col4a1 protein; collagen of basement membrane, alpha-1 chain; collagen IV, alpha-1 polypeptide; collagen alpha-1(IV) chain; COL4A1 NC1 domain; CO4A1_HUMAN; collagen Ⅳ; collagen type Ⅳ.

Host:  

Rabbit

Application:  

ELISA, IHC-P, IHC-F, FC, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P72148
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: COL4A3; Goodpasture Antigen; collagen type IV Alpha 3 Chain; ATS3A; collagen, type IV, Alpha 3 (Goodpasture Antigen); ATS3B; collagen Alpha-3(IV) Chain; ATS2; Tumstatin; ATS3; collagen IV, Alpha-3 Polypeptide; BFH2; collagen IV Alpha 3 Chain
Species:  
Source:  
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Cat. No.: HY-P75683
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: COL4A3; Goodpasture Antigen; collagen type IV Alpha 3 Chain; ATS3A; collagen, type IV, Alpha 3 (Goodpasture Antigen); ATS3B; collagen Alpha-3(IV) Chain; ATS2; Tumstatin; ATS3; collagen IV, Alpha-3 Polypeptide; BFH2; collagen IV Alpha 3 Chain
Species:  
Rat
Source:  
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Cat. No.: HY-P71444
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: COL4A1; COL4A1 Protein; collagen type IV Alpha 1 Chain; Arresten; collagen Alpha-1(IV) Chain; COL4A1s; collagen Of Basement Membrane, Alpha-1 Chain; PADMAL; collagen IV, Alpha-1 Polypeptide; BSVD1; collagen, type IV, Alpha 1; RATOR; COL4A1 NC1 Domain; BSV
Species:  
Source:  
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Cat. No.: HY-P704062
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: COL4A1; COL4A1 Protein; collagen type IV Alpha 1 Chain; Arresten; collagen Alpha-1(IV) Chain; COL4A1s; collagen Of Basement Membrane, Alpha-1 Chain; PADMAL; collagen IV, Alpha-1 Polypeptide; BSVD1; collagen, type IV, Alpha 1; RATOR; COL4A1 NC1 Domain; BSV
Species:  
Source:  
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Cat. No.: HY-P72147
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: COL4A2; collagen type IV Alpha 2; collagen type IV Alpha 2 Chain; BSVD2A; collagen Alpha-2(IV) Chain; BSVD2B; DKFZp686I14213; POREN2; Canstatin; BSVD2; FLJ22259; ICH
Species:  
Source:  
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Cat. No.: HY-P7886
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: COL3A1; Alpha-1 type III collagen; Prev. EDS4A; collagen, Fetal; Ehlers-Danlos Syndrome type IV, Autosomal Dominant; EDSVASC; collagen, type III, Alpha 1; PMGEDSV; collagen Alpha-1(III) Chain; collagen type III Alpha 1 Chain; Alpha1 (III) collagen
Species:  
Source:  
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