9001-12-1
Chemical Structure
Collagenase IV, Clostridium histolytica
Synonym(s): Collagenase, Type IV
- CAS No.: 9001-12-1
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Collagenase IV, Clostridium histolytica]
Biological Activity:
Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin.
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Collagenase IV, Clostridium histolytica | Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin. |
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Collagenase, Type VI | Collagenase, Type VI (EC 3.4.24.3) is a collagenase that can degrade type VI collagen. Type VI collagen is a component of cell membranes in various tissues (such as skin, heart, blood vessels, cartilage, and synovial fluid). Excessive collagenase can cause extracellular matrix lesions. Collagenase is also a biomarker for tumor invasion and metastasis. Collagenase, Type VI can specifically act on the peptide bond between proline and glycine. This feature can be used to quickly and sensitively detect its concentration level in experiments using corresponding modified electrodes. | |||||||||||||||||||||
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Collagenase (Type D, animal free) | Collagenase (Type D, animal free) does not contain animal-related components, and has collagenase and secondary protease activities similar to type 1 and type 2 collagenase. The activity of Collagenase (Type D, animal free) is higher than that of Collagenase (Type A, animal free). | |||||||||||||||||||||
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Collagenase, Type VII | Collagenase, Type VII (EC 3.4.24.3) is a collagenase that can be used to induce thalamic hemorrhage. | |||||||||||||||||||||
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Collagenase (Type B, filtered, animal free) | Collagenase (Type B, animal free) does not contain animal-related components, and is sterilized by filtration using a 0.22 μm filter membrane. Collagenase (Type B, filtered, animal free) has higher collagenase and casein activity. | |||||||||||||||||||||
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Collagenase I, from Clostridium histolyticum | Collagenases are enzymes that break the peptide bonds in collagen. Collagenases are derived from the Clostridium histolyticum. Collagenases (Type I) are proteolytic enzymes that break peptide bonds in collagen and can be used for tissue digestion and dissociation. | |||||||||||||||||||||
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Collagenase (Type A, animal free) | Collagenase (Type A, animal free) is a proteolytic enzyme targeting collagen, capable of releasing corneal endothelial cells (CECs) without damaging cell junctions. | |||||||||||||||||||||
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Collagenase, Type VIII | Collagenase, Type VIII is a mixed enzyme derived from Clostridium histolyticum that contains collagenase, a nonspecific protease, and a clostripain. Collagenase, Type VIII can hydrolyze Type VIII collagen and may be used to study the formation of atherosclerosis. Type VIII collagen is a regulator of endothelial cell differentiation and angiogenesis, a substrate for cell adhesion and migration such as smooth muscle cells, and may accumulate in atherosclerosis. After endotoxin activates the expression of Collagenase, Type VIII, it can reduce the production of Type VIII collagen and has the potential to inhibit atherosclerosis. | |||||||||||||||||||||
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Collagenase, Type III | Collagenase, Type III is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type III breaksdown collagens1, 4, 9, 10, 14, fibronectin, MMP-9, gelatin, plasminogen, aggrecan,perlecan osteonectin |
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Collagenase (Type A, filtered, animal free) | Collagenase (Type A, filtered, animal free) is a proteolytic enzyme targeting collagen, capable of releasing corneal endothelial cells (CECs) without damaging cell junctions. | |||||||||||||||||||||
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Collagenase (Type C, filtered, animal free) | Collagenase (Type C, filtered, animal free) does not contain animal-related components, and is sterilized by filtration using a 0.22 μm filter membrane. Collagenase (Type C, filtered, animal free) has low trypsin activity similar to type 4 collagenase. | |||||||||||||||||||||
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Collagenase, Type V | Collagenase, Type V is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type V breaksdown collagens1, 3, 5, 7, 8, 10, fibronectin, gelatin, aggrecann. |
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Collagenase, Type I | Collagenase, Type I is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type I breaks down collagens 1, 3, 7, 8, 10, gelatin, proteoglycans, aggrecan. |
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Collagenase, Type II | Collagenase, Type II is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type II breaksdown collagens1, 3, 5, 7, 8, 10, fibronectin, gelatin, aggrecann. |
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Collagenase (Type C, animal free) | Collagenase (Type C, animal free) is a proteolytic enzyme targeting collagen, capable of releasing corneal endothelial cells (CECs) without damaging cell junctions. | |||||||||||||||||||||
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Collagenase (Type B, animal free) | Collagenase (Type B, animal free) is a proteolytic enzyme targeting collagen, capable of releasing corneal endothelial cells (CECs) without damaging cell junctions. | |||||||||||||||||||||
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Keywords
- Collagenase IV, Clostridium histolytica
- Collagenase, Type VI
- Collagenase (Type D, animal free)
- Collagenase, Type VII
- Collagenase (Type B, filtered, animal free)
- Collagenase I, from Clostridium histolyticum
- Collagenase (Type A, animal free)
- Collagenase, Type VIII
- Collagenase, Type III
- Collagenase (Type A, filtered, animal free)
- Collagenase (Type C, filtered, animal free)
- Collagenase, Type V
- Collagenase, Type I
- Collagenase, Type II
- Collagenase (Type C, animal free)
- Collagenase (Type B, animal free)