Collagenase I, from Clostridium histolyticum
Based on 2 publication(s) in Google Scholar
Collagenases are enzymes that break the peptide bonds in collagen. Collagenases are derived from the Clostridium histolyticum. Collagenases (Type I) are proteolytic enzymes that break peptide bonds in collagen and can be used for tissue digestion and dissociation.
For research use only. We do not sell to patients.
- CAS No.: 9001-12-1
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Collagenase I, from Clostridium histolyticum
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Biological Activity
Collagenase is believed to be important for cell migration and collagen remodeling during tissue repair and regeneration. Activated collagenase produced the characteristic 3/4 fragment of collagen[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
3.4.24.3
≥125 U/mg soild
One unit liberates one micromole of L-leucine equivalents from collagen in 5 hours at 37°C, pH 7.5
Chemical Information
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CAS No. 9001-12-1
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Appearance Solid
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Color Light yellow to brown
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SMILES
[Collagenase I, from Clostridium histolyticum]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice. [Abstract]2025 Nov 11:e08957. PMID: 41215712 -
J Mol Cell Biol
Microtubule-associated CCDC112 is essential for spermiogenesis and male fertility in mice. [Abstract]2026 Jun 25:mjag019. PMID: 42348320
Solvent & Solubility
H2O : ≥ 50 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)