Frenolicin
Frenolicin is an antibiotic with antibacterial activity. Frenolicin also exhibits cytotoxicity against tumor cells.
For research use only. We do not sell to patients.
- CAS No.: 10023-07-1
- Formula: C18H18O7
- Molecular Weight:346.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
5.77 μM
Compound: 6
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Cytotoxicity against human A549 cells after 2 days by MTT assay
Cytotoxicity against human A549 cells after 2 days by MTT assay
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[PMID: 23944931] |
Chemical Information
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CAS No. 10023-07-1
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Molecular Weight 346.33
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Formula C18H18O7
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SMILES
O=C(O)C[C@@H]1C[C@](C(C2=C3C(O)=CC=C2)=O)(O4)[C@@]4(C3=O)[C@@H](CCC)O1
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Structure Classification
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Initial Source
Streptomyces fradiae (Lederle Number AC-860)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang X, et al. Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. J Nat Prod. 2013 Aug 23;76(8):1441-7. [Content Brief]
[2]. Bibb MJ, et al. Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin. Gene. 1994 May 3;142(1):31-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)