Verzistobart
Based on 1 Customer Validation
Verzistobart is an IgG1κ antibody targeting the hepatitis A virus cellular receptor HAVCR2.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 2649466-18-0
- Molecular Weight:144.089 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
HAVCR2
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG1 kappa
ELISA, FACS, Functional assay
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Immobilized TIM-3/HAVCR2 Protein, Human (HEK293, His, HY-P70482) can bind Verzistobart. The EC50 for this effect is 6.522 ng/mL. -
Flow cytometric analysis of 1X106 MCF-7 cells with Verzistobart (HY-P990085, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
Chemical Information
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CAS No. 2649466-18-0
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Appearance Liquid
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Molecular Weight 144.089 kDa
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Color Colorless to light yellow
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SMILES
[Verzistobart]
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Synonyms
INCAGN02390
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (229 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Inhibitory Antibodies User Guide (603 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)