2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N10986
    (±)-Hydnocarpin 298704-61-7 98%
    (±)-Hydnocarpin is a flavonolignan. (±)-Hydnocarpin can inhibit the growth of S. aureus with a MIC50 value of 3.1 μM.
    (±)-Hydnocarpin
  • HY-N10992
    Pomolic acid 3-acetate 15914-62-2 98%
    Pomolic acid 3-acetate is an antitubercular agent with a MIC of 32 μM against Mycobacterium tuberculosis H37Rv.
    Pomolic acid 3-acetate
  • HY-N11009
    11-Oxomogroside II A1 942612-74-0 98%
    11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.
    11-Oxomogroside II A1
  • HY-N11015
    Withaphysalin R 949172-12-7 98%
    Withaphysalin R (compound 5) is a Withanolide that can be isolated from the Solanaceae. Withanolide is a steroid ester with an ergosterol skeleton, and some of these compounds have some significant activities, including cytotoxic and immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant.
    Withaphysalin R
  • HY-N11020
    Cabenoside D 88901-40-0 98%
    Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation.
    Cabenoside D
  • HY-N11031
    Z-Antiepilepsirine 111479-04-0 98%
    Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC50 value of 27 µM for W2 strain of Plasmodium falciparum.
    Z-Antiepilepsirine
  • HY-N11048
    Amycolatopsin A 2209112-96-7 98%
    Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively.
    Amycolatopsin A
  • HY-N11054
    Psoracorylifol B 879290-98-9 98%
    Psoracorylifol B is a Helicobacter pylori inhibitor with MICs of both 12.5 μg/mL against H. pylori ATCC 43504 and H. pylori SS1.
    Psoracorylifol B
  • HY-N11056
    Justicidin C 17803-12-2 98%
    Justicidin C is an antiviral lignan. Justicidin C shows strong antiviral activity against vesicular stomatitis virus and low cytotoxicity against rabbit lung cells (RL-33).
    Justicidin C
  • HY-N11079
    Toonaciliatin M 93930-04-2 98%
    Toonaciliatin M (compound 6) is a pmaradiene-type diterpenoid that can be isolated from Toona ciliate. Toonaciliatin M show antifungal activity against Trichophyton rubrum with an MIC value of 12.5 µg/mL.
    Toonaciliatin M
  • HY-N11096
    Sinococuline 109351-36-2 98.29%
    Sinococuline is a potent anti-dengue agent that is effective against all four serotypes of dengue virus (DENV). Sinococuline is also an effective tumor cell growth inhibitor.
    Sinococuline
  • HY-N11097
    FK-3000 1054312-81-0 98%
    FK-3000 is a potent anti-tumor agent that inhibits the growth of carcinoma cells through apoptosis and induction cell cycle arrest. FK-3000 also exhibit antiviral effects against HSV-1 and HIV-1.
    FK-3000
  • HY-N11100
    Geranin A 226715-59-9 98%
    Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum.
    Geranin A
  • HY-N11137
    3′-Omethyl-5′-hydroxydiplacone 1005517-26-9 98%
    3′-Omethyl-5′-hydroxydiplacone (compound 2), an C-6-geranylflavonoid, can be isolated from the ethanol extract of Paulownia tomentosa fruits. 3′-Omethyl-5′-hydroxydiplacone has antibacterial activity against Gram-positive bacteria.
    3′-Omethyl-5′-hydroxydiplacone
  • HY-N11169
    Apigravin 72963-64-5 98%
    Apigravin is a potent antibacterial agent. Apigravin shows antibacterial activity against Bacillus subtilis with a MIC value of 61 μM.
    Apigravin
  • HY-N11241
    Cascaroside B 53861-34-0 98%
    Cascaroside B is a flavonoid and antifungal agent found in the Pseudomonas aeruginosa Ld-08.
    Cascaroside B
  • HY-N11259
    Sophoradiol 6822-47-5 98%
    Sophoradiol is a triterpenoid compound that can be extracted from Abrus Precatorius. Sophoradiol is an orally effective anti-tuberculosis agent. Sophoradiol has inhibitory activity against various strains of Mycobacterium tuberculosis. Sophoradiol has good biocompatibility. Sophoradiol can be used in the research of tuberculosis.
    Sophoradiol
  • HY-N1127R
    Tricin (Standard) 520-32-1 98%
    Tricin (Standard) is the analytical standard of Tricin. This product is intended for research and analytical applications. Tricin is a natural flavonoid found in large amounts in wheat. Tricin inhibits HCMV replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells by upregulating the expression of FAK-targeting microRNA-7 .
    Tricin (Standard)
  • HY-N11421
    23-O-Demycinosyltylosin 79592-92-0 98%
    23-O-Demycinosyltylosin (23-DMT) is a 23-O-demycinosyltylosin (DMT) acyl derivative with antibacterial activity.
    23-O-Demycinosyltylosin
  • HY-N11430
    F1839-I 159096-49-8 98%
    F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC50 value of 15.6 μM.
    F1839-I
Cat. No. Product Name / Synonyms Application Reactivity