129966-45-6
Chemical Structure
Kapurimycin A3
- CAS No.: 129966-45-6
- Formula:C27H24O9
- Molecular Weight:492.47
IUPAC Name: 2-((S)-8-acetoxy-12-hydroxy-2-((2S,3R)-2-methyl-3-((Z)-prop-1-en-1-yl)oxiran-2-yl)-4,11-dioxo-8,9,10,11-tetrahydro-4H-naphtho[2,3-h]chromen-5-yl)acetic acid
InChIKey: GMKMVBAGONGKOV-ANGZKDRVSA-N
SMILES: O=C(O)CC(C=C1C=C2[C@@H](OC(C)=O)CC3)=C(C(C=C([C@@]4(C)O[C@@H]4/C=C\C)O5)=O)C5=C1C(O)=C2C3=O
Biological Activity: Kapurimycin A3 is an antitumor and antibacterial antibiotic. Kapurimycin A3 has DNA binding and breakage activity. Kapurimycin A3 can be isolated from Streptomyces[1][2].
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Kapurimycin A3 | Kapurimycin A3 is an antitumor and antibacterial antibiotic. Kapurimycin A3 has DNA binding and breakage activity. Kapurimycin A3 can be isolated from Streptomyces. | |||||||||||||||||||||
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- [1]. Hara M, et al. Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3. Biochemistry. 1990 Nov 20;29(46):10449-55. [Content Brief]
- [2]. PRODUCING ORGANISM, et al. THE KAPURIMYCINS, NEW ANTITUMOR ANTIBIOTICS PRODUCED BY STREPTOMYCES. The Journal of Antibiotics. 1990. 43 (12), p. 1513-1518
Keywords