2987763-18-6
Chemical Structure
MtTMPK-IN-5
- CAS No.: 2987763-18-6
- Formula:C21H23N5O2
- Molecular Weight:377.44
IUPAC Name: 1-(1-([2,2'-bipyridin]-6-ylmethyl)piperidin-4-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: NFHHSDMJOLMBEV-UHFFFAOYSA-N
SMILES: CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=CC=CC(C4=CC=CC=N4)=N3
Biological Activity: MtTMPK-IN-5 (compound 17) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 34 μM. MtTMPK-IN-5 combines favorable enzyme inhibitory activity with significant activity against M. tuberculosis (MIC = 12.5 μM). MtTMPK-IN-5 can be used for researching tuberculosis[1].
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MtTMPK-IN-5 | MtTMPK-IN-5 (compound 17) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 34 μM. MtTMPK-IN-5 combines favorable enzyme inhibitory activity with significant activity against M. tuberculosis (MIC = 12.5 μM). MtTMPK-IN-5 can be used for researching tuberculosis. | |||||||||||||||||||||
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Keywords
