MtTMPK-IN-5
MtTMPK-IN-5 (compound 17) is a potent M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor with an IC50 value of 34 μM. MtTMPK-IN-5 combines favorable enzyme inhibitory activity with significant activity against M. tuberculosis (MIC = 12.5 μM). MtTMPK-IN-5 can be used for researching tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 2987763-18-6
- Formula: C21H23N5O2
- Molecular Weight:377.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 34 μM (MtbTMPK)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | CC50 |
>64 μM
Compound: 17
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Cytotoxicity against human MRC5 cells measured after 24 hrs by neutral red uptake assay
Cytotoxicity against human MRC5 cells measured after 24 hrs by neutral red uptake assay
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[PMID: 32823003] |
Chemical Information
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CAS No. 2987763-18-6
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Molecular Weight 377.44
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Formula C21H23N5O2
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SMILES
CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=CC=CC(C4=CC=CC=N4)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MtTMPK-IN-5 Related Classifications
HY-146699 Related Classifications
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