2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N11434
    Anisocoumarin H 123237-86-5
    Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL.
    Anisocoumarin H
  • HY-N11505
    Isopicropodophyllone 55515-07-6 98%
    Isopicropodophyllone, a natural compound that can be isolated from leaves of Podophyllum hexandrum, possesses antifungal activity.
    Isopicropodophyllone
  • HY-N11506
    lsocryptomerin 20931-58-2 98%
    lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities.
    lsocryptomerin
  • HY-N11528
    Eugenitol 491-48-5 98%
    Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii).
    Eugenitol
  • HY-N11550
    Salviandulin E 158994-32-2 98%
    Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL.
    Salviandulin E
  • HY-N11560
    9-Eicosenoic acid 506-31-0 98%
    9-Eicosenoic acid is a fatty acid (20:1ω11). 9-Eicosenoic acid can be isolated from Roseinatronobacter monicus strain ROS 10.
    9-Eicosenoic acid
  • HY-N11646
    Ganorbiformin B 1421611-59-7 98%
    Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra.
    Ganorbiformin B
  • HY-N11649
    Methyl lucidenate Q 648430-32-4 98%
    Methyl lucidenate Q is a methyl lucidenate. Methyl lucidenate Q shows potent inhibitory effects on EBV-EA induction.
    Methyl lucidenate Q
  • HY-N11650
    (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid 1846584-06-2 98%
    (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid (compound 15) is an antitubercular agent with MIC value of 12.5 μg/mL for Mycobacterium tuberculosis H37Ra. (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid shows cytotoxicity with IC50 value of 32 μM for Vero cells.
    (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid
  • HY-N11685
    (±)-Lomatin 1147-25-7 98%
    (±)-Lomatin (Xanthogalol) (Compound 10) is a coumarin-type secondary metabolite. (±)-Lomatin can be found in Coleonema album. (±)-Lomatin can be used for the research of bacterial infections, mycobacterial infections, and fungal infections.
    (±)-Lomatin
  • HY-N11706
    β-Cedrene 546-28-1 98.94%
    β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM.
    β-Cedrene
  • HY-N11719
    Clusin 86992-94-1 98%
    Clusin is a lignan that can be found in Hernandia nymphaeifolia. Clusin inhibits growth of the Gram-negative pathogen Neisseria gonorrhoeae. Clusin is inactive against murine lymphocytic leukemia cells and human cancer cells.
    Clusin
  • HY-N11723
    Catenarin 476-46-0 98%
    Catenarin, an anthraquinone compound, inhibits CCR5- and CXCR4-mediated chemotaxis. Catenarin reduces the phosphorylation of mitogen-activated protein kinases (p38 and JNK) and their upstream kinases (MKK6 and MKK7), and calcium mobilization. Catenarin shows anti-inflammatory effect and suppresses leukocyte migration in the diabetes. Catenarin exhibits significant inhibitory effects against Gram-positive bacteria. Catenarin prevents type 1 diabetes (T1D) in nonobese diabetic mice[1][2].
    Catenarin
  • HY-N11731
    Rotenonone 4439-62-7 98%
    Rotenonone is a derivative of Rotenone (HY-B1756), with a LD50 of 0.68 μg/g against larvae of Spodoptera litura.
    Rotenonone
  • HY-N11733
    D-Glucoheptose 62475-58-5 98%
    D-Glucoheptose is a heptose monosaccharide that serves as a starting material for sedoheptulose. D-Glucoheptose has a strong association with the genus Symbiobacterium. The content of D-Glucoheptose in urine of the control group without liver injury is higher than that in the anti-tuberculosis drug-induced liver injury group. D-Glucoheptose can be used in studies related to anti-tuberculosis drug-induced liver injury.
    D-Glucoheptose
  • HY-N11897
    4-Hydroxycinnamide 59576-98-6 98%
    4-Hydroxycinnamide is a new bacterial metabolite. 4-Hydroxycinnamide can be isolated from Streptomyces sp. PU-KB10-4.
    4-Hydroxycinnamide
  • HY-N11939
    Kadsuralignan A 913237-64-6 98%
    Kadsuralignan A (compound 1) is a dibenzocyclooctadiene lignan isolated from the leaves and stems of Schisandra lancifolia. Kadsuralignan A has anti-HIV activity with EC50=2.23 μg/mL.
    Kadsuralignan A
  • HY-N11940
    Acetyl-binankadsurin A 77174-33-5 98%
    Acetyl-binankadsurin A (compound 5) is a lignan isolated from Kadsura longipedunculata. Acetyl-binankadsurin A has low inhibitory activity against HIV-1 protease, with IC50 >100 μg/mL.
    Acetyl-binankadsurin A
  • HY-N11949
    Interiorin 119139-55-8 99.24%
    Interiorin can be isolated from Kadsura heteroclita and has moderate anti-HIV activity with an EC50 value of 1.6 lg/mL.
    Interiorin
  • HY-N11982
    Emeguisin A 117032-54-9 98%
    Emeguisin A is a depsidone with an antibacterial activity. Emeguisin A inhibits the human colon carcinoma (HCT-116) cell viability with rate of 87.06%.
    Emeguisin A
Cat. No. Product Name / Synonyms Application Reactivity