3043821-43-5
3043821-43-5
Chemical Structure
Antiparasitic agent-17
- CAS No.: 3043821-43-5
- Formula:C32H30N2O4
- Molecular Weight:506.59
IUPAC Name: 1-((2-hydroxy-5-oxo-2,5-dihydrofuran-3-yl)methyl)-5-(4-isopropylphenyl)-2-methyl-N,4-diphenyl-1H-pyrrole-3-carboxamide
InChIKey: SXIVDURMEMUDGS-UHFFFAOYSA-N
SMILES: CC(C)C1=CC=C(C2=C(C3=CC=CC=C3)C(C(NC4=CC=CC=C4)=O)=C(C)N2CC(C(O)O5)=CC5=O)C=C1
Biological Activity: Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively[1].
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Antiparasitic agent-17 | Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively. | |||||||||||||||||||||
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