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Cat. No.: HY-168656

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Ac-Atovaquone

Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria.

For research use only. We do not sell to patients.

CAS No.: 129700-44-3
Formula: C₂₄H₂₁ClO₄
Molecular Weight:408.87

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Ac-Atovaquone Chemical Structure

CAS No.: 129700-44-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria^[1]^[1]^[2].

All Parasite Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 129700-44-3
Molecular Weight 408.87
Formula C₂₄H₂₁ClO₄
SMILES

O=C1C([C@H]2CC[C@H](C3=CC=C(Cl)C=C3)CC2)=C(OC(C)=O)C(C4=CC=CC=C41)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Siqueira-Neto JL, et al. Antimalarial drug discovery: progress and approaches. Nat Rev Drug Discov. 2023 Oct;22(10):807-826. doi: 10.1038/s41573-023-00772-9. Epub 2023 Aug 31. Erratum in: Nat Rev Drug Discov. 2024 Nov;23(11):880.

[2]. El Gaaloul M, et al. Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile. Malar J. 2024 Oct 18;23(1):315. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References

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Ac-Atovaquone

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ac-Atovaquone Related Classifications

HY-168656 Related Classifications