229153-17-7
Chemical Structure
SS-750
- CAS No.: 229153-17-7
- Formula:C13H13F4N3O3S
- Molecular Weight:367.32
IUPAC Name: (R)-2-(2,4-difluorophenyl)-1-(ethylsulfonyl)-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)propan-2-ol
InChIKey: IXUDUJWKLANEIT-LBPRGKRZSA-N
SMILES: CCS(C(F)(F)[C@@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O
Biological Activity: SS-750 is an orally active Triazole derivative and antifungal agent. SS-750 binds to fungal cytochrome P450. SS-750 shows antifungal activities against Candida species and C. neoformans strains tested. SS750 shows MIC90 values of 0.25, 1, and 2 μg/mL against Candida parapsilosis, C. krusei, and C. glabrata, respectively. SS-750 improves systemic and pulmonary candidiasis caused by C. albicans[1].
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SS-750 | SS-750 is an orally active Triazole derivative and antifungal agent. SS-750 binds to fungal cytochrome P450. SS-750 shows antifungal activities against Candida species and C. neoformans strains tested. SS750 shows MIC90 values of 0.25, 1, and 2 μg/mL against Candida parapsilosis, C. krusei, and C. glabrata, respectively. SS-750 improves systemic and pulmonary candidiasis caused by C. albicans. | |||||||||||||||||||||
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