2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N10786
    1,3,6-Trihydroxy-5-methoxyxanthone 41357-84-0 98%
    1,3,6-Trihydroxy-5-methoxyxanthone is a nature product that could be isolated form the root bark of Tovomita krukovii. 1,3,6-Trihydroxy-5-methoxyxanthone has anti-fungal effect.
    1,3,6-Trihydroxy-5-methoxyxanthone
  • HY-N10791
    Neobritannilactone B 886990-00-7 98%
    Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. Neobritannilactone B is cytotoxic. Other extracts of I. britannica are also Dihydrofolate reductase (DHFR) inhibitors, which inhibit Shigella dysenteriae type 1.
    Neobritannilactone B
  • HY-N10801
    Salvianan A 2162956-63-8 98%
    1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) is a potent anti-HIV-1 agent.
    Salvianan A
  • HY-N10820
    Psoracorylifol C 879290-99-0 98%
    Psoracorylifol C is a natural product. Psoracorylifol C has important activity against Helicobacter pylori. Psoracorylifol C can be isolated from the seeds of Psoralea corylifolia.
    Psoracorylifol C
  • HY-N10830
    (±)-Nirtetralin 78185-63-4 98%
    (±)-Nirtetralin is an isomer of Nirtetralin, which inhibits growth of hepatitis E virus (HEV) in HepaRG cells.
    (±)-Nirtetralin
  • HY-N10834
    (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol 120166-71-4 98%
    (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be isolated from the roots of Atractylodes japonica. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol has anti-methicillin-resistant Staphylococcus aureus (MRSA) activity with MIC values of 4-32 μg/mL. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be used for the research of bacterial infection. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol
  • HY-N10837
    rel-3R-Methoxy-4S-furanogermacra-1E,10(15)-dien-6-one 1393342-06-7 98%
    rel-3-Methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one (compound 4) is a natural product that can be found in Commiphora erythraea.
    rel-3R-Methoxy-4S-furanogermacra-1E,10(15)-dien-6-one
  • HY-N10843
    4-O-Methylepisappanol 112529-37-0 98%
    4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively.
    4-O-Methylepisappanol
  • HY-N10863
    Aurantiamide benzoate 150881-02-0 99.07%
    Aurantiamide benzoate is a nature product that could be isolated from two tropical medicinal plants, Cunila spicata and Hyptis fasciculata. Aurantiamide benzoate is a potent xanthine oxidase inhiobitor with an IC50 value of 70 μM.
    Aurantiamide benzoate
  • HY-N10899
    Bruceine J 948038-38-8 98%
    Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity.
    Bruceine J
  • HY-N10900
    Bruceine C 25514-30-1 98%
    Bruceine C, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine C has anti-Babesial activity.
    Bruceine C
  • HY-N10905
    Rabdoserrin A 96685-01-7 98%
    Rabdoserrin A is a diterpenoid. Rabdoserrin A has antifungal activity.
    Rabdoserrin A
  • HY-N10907
    4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- 182056-11-7 98%
    4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2) is a quinolone alkaloid that can be isolated from Cnidium. 4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- has methicillin-resistant Staphylococcus aureus (MRSA) activity, with MIC values of 32 μg/mL (ATCC 33591) and 16 μM/mL (ATCC 25923), respectively.
    4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-
  • HY-N10912
    Shizukanolide 70578-36-8 98%
    Shizukanolide, a sesquiterpene lactone, can be isolated from Chloranthus japonicus (Chloranthaceae). The dehydro-compound of Shizukanolide, shows moderate antifungal activity.
    Shizukanolide
  • HY-N10920
    Genkwanol C 151283-11-3 98%
    Genkwanol C, a biflavonoid, has effective antiviral activity against respiratory syncytial virus (RSV) in vitro.
    Genkwanol C
  • HY-N10928
    Lettowienolide 1189105-39-2 98%
    Lettowienolide, a geranylbenzoquinonoid, exhibits mild in vitro activity against the Plasmodium falciparum malaria parasite (IC50~20 μg/mL).
    Lettowienolide
  • HY-N10930
    7-Oxo-ganoderic acid Z 929248-72-6 98%
    7-Oxo-ganoderic acid Z, a terpenoid, is a nature product that could be isolated from Resina Commiphora. 7-Oxo-ganoderic acid Z has Anti-Mycobacterium tuberculosis activity.
    7-Oxo-ganoderic acid Z
  • HY-N10934
    Ganoderic acid GS-1 1206781-64-7 98%
    Ganoderic acid GS-1, a highly oxygenated lanostane-type triterpenoid, has anti-HIV-1 protease activities with an IC50 of 58 μM.
    Ganoderic acid GS-1
  • HY-N10939
    Gluco-obtusin 960135-79-9 98%
    Gluco-obtusin is an anthraquinone. Gluco-obtusin can be isolated from the seeds of Cassia obtusifolia.
    Gluco-obtusin
  • HY-N10958
    Wikstrol A 159736-35-3 98%
    Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM.
    Wikstrol A
Cat. No. Product Name / Synonyms Application Reactivity