1. Anti-infection
  2. Fungal
  3. Antifungal agent 42

Antifungal agent 42 

Cat. No.: HY-151440
Handling Instructions

Antifungal agent 42 is an antifungal agent. Antifungal agent 42 has an inhibitory effect on lanosterol 14α-demethylase (CYP51) of C.alb.. Antifungal agent 42 inhibits biofilm formation.

For research use only. We do not sell to patients.

Antifungal agent 42 Chemical Structure

Antifungal agent 42 Chemical Structure

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Description

Antifungal agent 42 is an antifungal agent. Antifungal agent 42 has an inhibitory effect on lanosterol 14α-demethylase (CYP51) of C.alb.. Antifungal agent 42 inhibits biofilm formation[1].

IC50 & Target

CYP51[1]

In Vitro

Antifungal agent 42 (compound B03, 0.25-128 μg/mL) inhibits fungal activity with MIC values of 1-64 μg/mL[1].
Antifungal agent 42 (0.5 μg/mL, 1.5-24 h) displays antibiofilm activity against FCZ-Resistant C.alb[1].
Antifungal agent 42 (0-20 μM approximately) shows cytotoxicity against HL-60, MDA-MB-231 and PC-3 cells with IC50 values of 12.5, 5.5, 2.91 μM respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

569.25

Formula

C22H20Cl2N4Se2

SMILES

ClC1=CC=C(C([Se][Se]C(C2=CC=C(Cl)C=C2)CN3C=CN=C3)CN4C=CN=C4)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Antifungal agent 42
Cat. No.:
HY-151440
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