Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
Références:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Produits associés (4620)
Produits associés (4620)
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(3,4-Dimethoxyphenyl)hydrazine hydrochloride
0 Images(3,4-Dimethoxyphenyl)hydrazine hydrochloride is a drug intermediate for synthesis of various active compounds.
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2-(Hydroxy(4-phenoxyphenyl)methylene)malononitrile
0 ImagesCat. No.: HY-78855CAS No.: 330792-68-22-(Hydroxy(4-phenoxyphenyl)methylene)malononitrile is a drug intermediate for synthesis of various active compounds.
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(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
0 Images(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid is a drug intermediate for synthesis of various active compounds.
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O-Benzyl posaconazole
0 ImagesSynonyms: 4-[4-[4-[4-[[(3r,5r)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2s,3s)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-oneO-Benzyl posaconazole (4-[4-[4-[4-[[(3r,5r)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2s,3s)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-one) is a drug intermediate for synthesis of various active compounds.
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1-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
![1-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide](https://file.medchemexpress.com/product_pic/hy-i0462.gif "Click to View 1-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide Product Detail")
0 Images1-(4-Chlorophenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is a drug intermediate for synthesis of various active compounds.
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4-Carboxypyrazole
0 Images4-Carboxypyrazole (1H-Pyrazole-4-carboxylic acid) is a metabolite of Fomepizole (HY-B0876). 4-Carboxypyrazole is involved in the synthesis of ALKBH1 inhibitors. 4-Carboxypyrazole can be used in the research of gastric cancer.
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N-Boc-4-piperidinemethanol
0 ImagesN-Boc-4-piperidinemethanol (Compound 4) is a synthetic intermediate. N-Boc-4-piperidinemethanol can be used for the preparation of Acetylcholinesterase inhibitors.
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2-Chlorobenzoxazole
0 Images2-Chlorobenzoxazole is a synthetic building block that can be used to synthesize a variety of active compounds.
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2-Bromo-5-fluoropyridine
0 Images2-Bromo-5-fluoropyridine acts as a bromofluoropyridine starting material and an azaaryl halide coupling partner. 2-Bromo-5-fluoropyridine participates in an oxygen-promoted, ligand-free Pd (OAc)2-catalyzed Suzuki reaction, reacting with arylboronic acids to produce 5-fluoro-2-aryl-substituted pyridine derivatives. 2-Bromo-5-fluoropyridine can be used to synthesize 5-fluoro-2-(4-(methylsulfonyl) phenyl) pyridine, an intermediate of the GPR119 agonist GSK1292263A.
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4-trans-Hydroxycyclohexylamine
0 ImagesSynonyms: trans-4-Aminocyclohexan-1-ol4-trans-Hydroxycyclohexylamine (trans-4-Aminocyclohexan-1-ol) is an intermediate. 4-trans-Hydroxycyclohexylamine can be used in the synthesis of norepinephrine transporter inhibitors. 4-trans-Hydroxycyclohexylamine can be used in the research of mood and behavior-related diseases.
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2-Methylpropane-2-sulfinamide
0 Images2-Methylpropane-2-sulfinamide is an amide compound that can be used as an intermediate in pharmaceutical synthesis.
![4-Chloro-7H-pyrrolo[2,3-d]pyrimidine](https://file.medchemexpress.com/product_pic/hy-40351.gif "Click to View 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Product Detail")
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2-Methoxycarbonylphenylboronic acid
0 Images2-Methoxycarbonylphenylboronic acid is an intermediate. 2-Methoxycarbonylphenylboronic acid can be used in the synthesis of BLT2 agonist.
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Cyclohexane-1,3-dione
0 ImagesCyclohexane-1,3-dione is a drug intermediate, and its derivatives can exhibit significant tyrosine kinase inhibitory activity and anti-tumor activity.
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6-Methylsalicylic acid
0 Images6-Methylsalicylic acid is the secondary metabolite that could be isolated from some fungi. 6-Methylsalicylic acid can be used as building blocks for synthesis of antibacterial and anti-inflammatory agents.
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2,2-Dihydroxyacetic acid
0 Images2,2-Dihydroxyacetic acid is an endogenous metabolite, which is the monohydrate of Glyoxylic Acid. 2,2-Dihydroxyacetic acid may participate in the microbial glyoxylate cycle, induce an increase in reactive oxygen species, promote cell differentiation, and modify proteins to form advanced glycation end products (AGEs) (HY-NP165). 2,2-Dihydroxyacetic acid is associated with metabolic diseases such as primary hyperoxaluria.
