37718-11-9
37718-11-9
Chemical Structure
4-Carboxypyrazole
- CAS No.: 37718-11-9
- Formula:C4H4N2O2
- Molecular Weight:112.09
IUPAC Name: 1H-pyrazole-4-carboxylic acid
InChIKey: IMBBXSASDSZJSX-UHFFFAOYSA-N
SMILES: O=C(C1=CNN=C1)O
Biological Activity: 4-Carboxypyrazole (1H-Pyrazole-4-carboxylic acid) is a metabolite of Fomepizole (HY-B0876). 4-Carboxypyrazole is involved in the synthesis of ALKBH1 inhibitors. 4-Carboxypyrazole can be used in the research of gastric cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
4-Carboxypyrazole | 99.49% | 4-Carboxypyrazole (1H-Pyrazole-4-carboxylic acid) is a metabolite of Fomepizole (HY-B0876). 4-Carboxypyrazole is involved in the synthesis of ALKBH1 inhibitors. 4-Carboxypyrazole can be used in the research of gastric cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
4-Carboxypyrazole (Standard) | ≥98% | 4-Carboxypyrazole is an endogenous metabolite. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. McMartin KE, et al. Kinetics and metabolism of fomepizole in healthy humans. Clin Toxicol (Phila). 2012 Jun;50(5):375-83. [Content Brief]
- [2]. Li F, et al. Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity. J Med Chem. 2024 Sep 12;67(17):15456-15475. [Content Brief]
