27489-62-9
27489-62-9
Chemical Structure
4-trans-Hydroxycyclohexylamine
Synonym(s): trans-4-Aminocyclohexan-1-ol
- CAS No.: 27489-62-9
- Formula:C6H13NO
- Molecular Weight:115.17
IUPAC Name: (1r,4r)-4-aminocyclohexan-1-ol
InChIKey: IMLXLGZJLAOKJN-IZLXSQMJSA-N
SMILES: N[C@H]1CC[C@H](O)CC1
Biological Activity: 4-trans-Hydroxycyclohexylamine (trans-4-Aminocyclohexan-1-ol) is an intermediate. 4-trans-Hydroxycyclohexylamine is used in the synthesis of the PGK1 inhibitor Compd 25-4. 4-trans-Hydroxycyclohexylamine is used in research on EGFR-positive esophageal squamous cell carcinoma[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-trans-Hydroxycyclohexylamine | 99.98% | 4-trans-Hydroxycyclohexylamine (trans-4-Aminocyclohexan-1-ol) is an intermediate. 4-trans-Hydroxycyclohexylamine is used in the synthesis of the PGK1 inhibitor Compd 25-4. 4-trans-Hydroxycyclohexylamine is used in research on EGFR-positive esophageal squamous cell carcinoma. | ||||||||||||||||||||
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References
- [1]. Ge J, et al. Pharmacological inhibition of PGK1 suppresses EGFR-positive esophageal squamous cell carcinoma by dual targeting of glycolysis and autophagy-dependent EGFR degradation. Cellular oncology (Dordrecht, Netherlands). 2026 Apr 29;49(3):82. [Content Brief]
- [2]. Deretic V, et al. Enhancement of lung levels of antibiotics by ambroxol and bromhexine. Expert opinion on drug metabolism & toxicology. 2019 Mar;15(3):213-218. [Content Brief]
