Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4632)
Related Products (4632)
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21-Chloro-3,6,9,12,15-pentaoxahenicosan-1-ol
0 ImagesCat. No.: HY-43132CAS No.: 1355956-01-221-Chloro-3,6,9,12,15-pentaoxahenicosan-1-ol is a drug intermediate for synthesis of various active compounds.
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5-Fluoro-2-methylpyridin-3-amine
0 Images5-Fluoro-2-methylpyridin-3-amine is a drug intermediate for synthesis of various active compounds.
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3-Methoxyisoquinoline-1-carboxylic acid
0 Images3-Methoxyisoquinoline-1-carboxylic acid is a drug intermediate for synthesis of various active compounds.
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2-((1s,4s)-4-Phenylcyclohexyl)acetic acid
0 Images2-((1s,4s)-4-Phenylcyclohexyl)acetic acid is a drug intermediate for synthesis of various active compounds.
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Umeclidinium bromide impurity 8
0 ImagesCat. No.: HY-W004415CAS No.: 55022-88-3Umeclidinium bromide impurity 8 is an impurity of Umeclidinium Bromide (HY-12100).
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BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid
0 ImagesSynonyms: (1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acidBoc-(1S,3R)-3-aminocyclopentanecarboxylic acid ((1S,3R)-3-[(tert-butoxycarbonyl)amino]cyclopentanecarboxylic acid) is an intermediate used in chemical synthesis.
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4,4'-(6-Chloropyrimidine-2,4-diyl)dimorpholine
0 ImagesCat. No.: HY-75511CAS No.: 10244-24-34,4'-(6-Chloropyrimidine-2,4-diyl)dimorpholine is a drug intermediate for synthesis of various active compounds.
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(5-Methyl-1-Tritylimidazol-4-yl)Methanol
0 Images(5-Methyl-1-Tritylimidazol-4-yl)Methanol is a drug intermediate for synthesis of various active compounds.
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Quetiapine impurity 25
0 ImagesQuetiapine impurity 25 is an impurity of Quetiapine.
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Sildenafil impurity 1
0 ImagesSynonyms: Sildenafil N-Oxide Impurity
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Zotadirsen
0 ImagesCat. No.: HY-177972Zotadirsen is the core component of the AOC drug Delpacibart zotadirsen (AOC1044) (HY-177564), consisting of a phosphorodiamidate morpholino oligonucleotide (PMO) targeting exon 44 of the dystrophin gene and an SMCC linker (HY-42360). Upon conjugation with the anti-TfR1 antibody Delpacibart (HY-P990051), Zotadirsen exerts splicing regulatory activity and mediates exon skipping. Zotadirsen can be used in studies related to AOC synthesis.
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Linaprazan glurate
0 ImagesSynonyms: X842Linaprazan glurate (X842) is an orally atcive prodrug of Linaprazan (HY-100412) with a potent and prolonged inhibitory effect on gastric acid secretion. Linaprazan glurate is rapidly transformed by enzymatic cleavage into its active metabolite, linaprazan. Linaprazan glurate is a potassium-competitive acid blocker. Linaprazan glurate selectively inhibites acid formation from gastric H⁺/K⁺-ATPase in a potassium-dependent manner (IC50 = 436.2 nM). Linaprazan glurate can be used for the studies of erosive esophagitis (EE).
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Avibactam tomilopil
0 ImagesSynonyms: ARX-1796; AV-006Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections.
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Pixavir marboxil
0 ImagesSynonyms: TG-1000Pixavir marboxilo (TG-1000) is an orally active prodrug of TG-0527 and an analog of Baloxavir marboxil (HY-109025). Pixavir marboxilo undergoes conversion to its active metabolite and inhibits the cap‑dependent endonuclease of Influenza Virus, reduces pulmonary viral titers, and suppresses the proliferation of influenza A, influenza B, H7N9 avian influenza, and neuraminidase‑resistant strains. Pixavir marboxilo can be used in influenza-related research.
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1,3,5-Tri(1H-1,2,3-triazol-5-yl)benzene
0 ImagesCat. No.: HY-W543267CAS No.: 1167993-47-61,3,5-Tri (1H-1,2,3-triazol-5-yl) benzene is a tritopic triazole-bridged ligand (H3BTTri) that forms a sodalite-type metal-organic framework with coordinatively unsaturated cobalt (II) centers. This framework exhibits selective O2-binding capacity over N2. 1,3,5-Tri (1H-1,2,3-triazol-5-yl) benzene can be used for the synthesis of metal-organic framework (MOF)-related materials.
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Trihydroxycoprostane
0 ImagesCat. No.: HY-W740611CAS No.: 547-96-6Trihydroxycoprostane (THCP) is a polyhydroxysterane compound with a 5β configuration. ITrihydroxycoprostane acts as a key intermediate in the biosynthesis of bile acids from cholesterol and also serves as an important sterol metabolite generated by host-gut microbiota interactions. Trihydroxycoprostane can be used for mechanistic studies of diseases such as non-alcoholic fatty liver disease, inflammatory bowel disease, and bile acid metabolism disorders.
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Budesonide oleate (C18:1)
0 ImagesSynonyms: Budesonide 21-oleateBudesonide oleate (C18:1) (Budesonide 21-oleate) is a prodrug of Budesonide (HY-13580), and can be used as the active ingredient of anti-inflammatory lipid nanoparticles for targeted delivery of anti-inflammatory agents.
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Desmethyl nevanimibe
0 ImagesDesmethyl nevanimibe (Compound 5) is the demethyl precursor of the sterol O-acyltransferase 1 (SOAT1) inhibitor Nevanimibe (PD-132301).
