1. Antibody-drug Conjugate/ADC Related Apoptosis Cytoskeleton
  2. Transferrin Receptor Antibody-Oligonucleotide Conjugates (AOCs) Dystrophin
  3. Delpacibart zotadirsen

Delpacibart zotadirsen  (Synonyms: Del-zota; AOC 1044)

Cat. No.: HY-177564
Handling Instructions Technical Support

Delpacibart zotadirsen (Del-zota), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated to a phosphorodiamidate morpholino conjugate (PMO), Delpacibart zotadirsen is designed to deliver phosphorodiamidate morpholino oligomers (PMOs) to skeletal muscle and heart tissue to specifically skip exon 44 of the dystrophin gene and enable production of near-full length dystrophin. Delpacibart zotadirsen is used for the study of myotonic dystrophy type 1 (DM1).

For research use only. We do not sell to patients.

Delpacibart zotadirsen

Delpacibart zotadirsen Chemical Structure

CAS No. : 2929240-20-8

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Description

Delpacibart zotadirsen (Del-zota), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated to a phosphorodiamidate morpholino conjugate (PMO), Delpacibart zotadirsen is designed to deliver phosphorodiamidate morpholino oligomers (PMOs) to skeletal muscle and heart tissue to specifically skip exon 44 of the dystrophin gene and enable production of near-full length dystrophin. Delpacibart zotadirsen is used for the study of myotonic dystrophy type 1 (DM1)[1].

In Vitro

Delpacibart zotadirsen is primarily used in the study of Duchenne muscular dystrophy with exon 44 skipping mutations (DMD44), and can cover both ambulatory and non-ambulatory patients aged 7-27 years[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
SMILES

[Delpacibart zotadirsen]

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Delpacibart zotadirsen
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