Oligonucleotide-Linker Conjugates for AOC
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Oligonucleotide-Linker Conjugates for AOC Related Products (16)
Related Products (16)
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Etedesiran
0 ImagesCat. No.: HY-147262Etedesiran is a component of the AOC drug Delpacibart etedesiran (HY-177565), formed by the reaction of an siRNA that induces cleavage of mRNA encoding myotonic dystrophy protein kinase (MTPK or DMPK) with SMCC linker (HY-42360). Etedesiran carries a maleimide group at its terminus, which can react with cysteine or lysine and is used for the synthesis of AOC drugs. Etedesiran is applicable to research related to myotonic dystrophy type 1.
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Braxlosiran
0 ImagesCat. No.: HY-177971Braxlosiran is a component of the AOC reagent Delpacibart braxlosiran (HY-177566), consisting of an siRNA targeting DUX4 (double homeobox protein) and SMCC linker (HY-42360). Delpacibart braxlosiran binds to TfR1. Aberrant expression of the DUX4 protein causes changes in gene expression in muscle cells, which are associated with muscle function loss in facioscapulohumeral muscular dystrophy (FSHD).
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Zotadirsen
0 ImagesCat. No.: HY-177972Zotadirsen is the core component of the AOC drug Delpacibart zotadirsen (AOC1044) (HY-177564), consisting of a phosphorodiamidate morpholino oligonucleotide (PMO) targeting exon 44 of the dystrophin gene and an SMCC linker (HY-42360). Upon conjugation with the anti-TfR1 antibody Delpacibart (HY-P990051), Zotadirsen exerts splicing regulatory activity and mediates exon skipping. Zotadirsen can be used in studies related to AOC synthesis.
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FAM labled Zotadirsen
0 ImagesCat. No.: HY-177972BFAM labled Zotadirsenis a FAM labled Zotadirsen.
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FAM labled Zoratolimod
0 ImagesCat. No.: HY-177973BFAM labled Zoratolimodis a FAM labled Zoratolimod.
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Cy3 labled Zoratolimod
0 ImagesCat. No.: HY-177973CCy3 labled Zoratolimod is a Cy3 labled Zoratolimod.
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Zoratolimod scrambled negative control
0 ImagesCat. No.: HY-177973AZoratolimod scrambled negative control is the sequence scrambled negative control of Zoratolimod.
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Braxlosiran scrambled negative control
0 ImagesCat. No.: HY-177971ABraxlosiran scrambled negative control is the sequence scrambled negative control of Braxlosiran.
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Cy3 labled Braxlosiran
0 ImagesCat. No.: HY-177971CCy3 labled Braxlosiran is a Cy3 labled Braxlosiran.
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FAM labled Braxlosiran
0 ImagesCat. No.: HY-177971BFAM labled Braxlosiranis a FAM labled Braxlosiran.
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Zoratolimod
0 ImagesCat. No.: HY-177973Zoratolimod is a component of the AOC reagent Mozistobart zoratolimod (HY-177568), consisting of a TLR9 agonist and a linker Fmoc-N-PEG24-acid (HY-42360).is a TLR9 agonist. Zoratolimod can be used to synthesize antibody oligonucleotide conjugates (AOC) such as Mozistobart zoratolimod, which is used in cancer immunology research.
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Zotadirsen scrambled negative control
0 ImagesCat. No.: HY-177972AZotadirsen scrambled negative control is the sequence scrambled negative control of Zotadirsen.
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Cy3 labled Zotadirsen
0 ImagesCat. No.: HY-177972CCy3 labled Zotadirsen is a Cy3 labled Zotadirsen.
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Etedesiran scrambled negative control
0 ImagesCat. No.: HY-147262AEtedesiran scrambled negative control is the sequence scrambled negative control of Etedesiran.
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FAM labled Etedesiran
0 ImagesCat. No.: HY-147262BFAM labled Etedesiranis a FAM labled Etedesiran.
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Cy3 labled Etedesiran
0 ImagesCat. No.: HY-147262CCy3 labled Etedesiran is a Cy3 labled Etedesiran.
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